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首页> 外文期刊>Polymers for advanced technologies >Layer-by-layer deposition of antimicrobial polymers on cellulosic fibers: a new strategy to develop bioactive textiles
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Layer-by-layer deposition of antimicrobial polymers on cellulosic fibers: a new strategy to develop bioactive textiles

机译：抗菌聚合物在纤维素纤维上的逐层沉积：开发生物活性纺织品的新策略

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摘要

In recent years, there has been an increase of infectious diseases caused by different microorganisms and the development of antibiotic resistance. In this way, the search for new and efficient antibacterial materials is imperative. The main polysaccharides currently used in the biomedical and pharmaceutical domains are chitin and its derivative chitosan (CH) and alginates (ALG). In this study, a simple technique of Layer by Layer (LbL) of applying polycation CH and polyanion ALG was used to prepare CH/ALG multilayers on cotton samples via the electrostatic assembly with success. The CH/ALG cotton samples (functionalized) were investigated for their antibacterial properties towards Staphylococcus aureus and Klebsiella pneumonia using the international standard method JIS L 1902:2002. The antibacterial activity of the functionalized samples was tested in terms of bacteriostatic and bactericidal activity, and results showed that the samples exhibited a bacteriostatic effect on the two bacteria tested, as expected. In addition, samples with five layers (CH/ALG/CH/ALG/CH) were more effective in inhibiting bacterial growth. This new coating for cellulosic fibers is a new strategy and may open new avenues for the development of antimicrobial polymers with potential application in health-care field.
机译：近年来，由不同微生物引起的传染病的增加和对抗生素的抗性的发展。这样，寻找新的和有效的抗菌材料势在必行。当前在生物医学和药学领域中使用的主要多糖是几丁质及其衍生物壳聚糖（CH）和藻酸盐（ALG）。在这项研究中，使用聚阳离子CH和聚阴离子ALG的一种简单的逐层（LbL）技术成功地通过静电组装在棉样上制备了CH / ALG多层。使用国际标准方法JIS L 1902：2002对CH / ALG棉样品（功能化）对金黄色葡萄球菌和肺炎克雷伯菌的抗菌性能进行了研究。按照抑菌和杀菌活性测试了功能化样品的抗菌活性，结果表明，样品与预期的两种细菌均表现出抑菌作用。另外，五层样品（CH / ALG / CH / ALG / CH）在抑制细菌生长方面更有效。这种用于纤维素纤维的新型涂层是一种新策略，并可能为开发抗菌素聚合物开辟新途径，并有望在医疗保健领域中应用。

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