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首页> 外文期刊>Paediatric and perinatal epidemiology >Necrotising enterocolitis hospitalisations among neonates in the United States.
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Necrotising enterocolitis hospitalisations among neonates in the United States.

机译:在美国,新生儿坏死性小肠结肠炎的住院治疗。

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The objective of this study was to estimate the rate and describe the epidemiology of necrotising enterocolitis (NEC) among neonates (infants <1 month of age) hospitalised in the United States. Hospital discharge records for neonates with an NEC diagnosis and an in-hospital death or routine discharge were selected for analysis from the 2000 Kids' Inpatient Database. An estimated 4463 (SE = 219) hospitalisations associated with NEC occurred among neonates in the United States during the year 2000, resulting in a hospitalisation rate of 109.9 [95% CI 97.2, 122.6] per 100 000 livebirths. The rate of NEC hospitalisations was highest among non-Hispanic Black neonates. The median hospital length of stay was 49 days. The in-hospital fatality rate was 15.2% (SE = 1.0%). Neonates who underwent a surgical procedure during hospitalisation were more likely to have a longer length of stay and to die than were those who did not have surgical intervention. Low-birthweight (LBW) neonates with NEC were more likely thanLBW neonates hospitalised with other diagnoses to be very LBW (VLBW), non-Hispanic Black and male. In addition, compared with LBW neonates hospitalised with other diagnoses, LBW neonates with NEC had higher hospital charges and longer lengths of stay, and were more likely to die during hospitalisation. This study provides the first national estimate of the rate of hospitalisation for NEC among neonates in the United States. During 2000, there was one NEC hospitalisation per 1000 livebirths, with approximately 1 in 7 NEC hospitalisations ending in death. NEC accounts for substantial morbidity; thus, the development of prevention strategies and effective therapies continues to be an important issue.
机译:这项研究的目的是评估在美国住院的新生儿(年龄<1个月的婴儿)的坏死性小肠结肠炎(NEC)的流行病学并进行描述。从2000年儿童住院数据库中选择了NEC诊断为新生儿,住院死亡或常规出院的新生儿出院记录进行分析。在2000年期间,美国新生儿中估计有4463例(SE = 219)与NEC相关的住院治疗,导致每10万活产儿的住院率为109.9 [95%CI 97.2,122.6]。在非西班牙裔黑人新生儿中,NEC的住院率最高。中位住院时间为49天。住院死亡率为15.2%(SE = 1.0%)。与未进行手术干预的新生儿相比,在住院期间接受外科手术的新生儿更有可能有更长的住院时间和死亡。与接受其他诊断后住院的LBW新生儿相比,低出生体重(LBW)的新生儿更有可能是LBW(VLBW),非西班牙裔黑人和男性。此外,与通过其他诊断住院的LBW新生儿相比,NEC的LBW新生儿住院费用更高,住院时间更长,并且在住院期间死亡的可能性更高。这项研究首次对美国新生儿NEC的住院率进行了全国性的估算。在2000年期间,每1000例婴儿中就有1例NEC住院,其中约有7例NEC住院死亡。 NEC导致大量发病。因此,预防策略和有效疗法的发展仍然是重要的问题。

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