• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Plasmid: An International Journal Devoted to Extrachromosomal Gene Systems >Cell-cell signaling and the Agrobacterium tumefaciens Ti plasmid copy number fluctuations.
【24h】

Cell-cell signaling and the Agrobacterium tumefaciens Ti plasmid copy number fluctuations.

机译：细胞信号转导和根癌农杆菌Ti质粒拷贝数波动。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

The Agrobacterium tumefaciens oncogenic Ti plasmids replicate and segregate to daughter cells via repABC cassettes, in which repA and repB are plasmid partitioning genes and repC encodes the replication initiator protein. repABC cassettes are encountered in a growing number of plasmids and chromosomes of the alpha-proteobacteria, and findings from particular representatives of agrobacteria, rhizobia and Paracoccus have began to shed light on their structure and functions. Amongst repABC replicons, Ti plasmids and particularly the octopine-type Ti have recently stood as model in regulation of repABC basal expression, which acts in plasmid copy number control, but also appear to undergo pronounced up-regulation of repABC, upon interbacterial and host-bacterial signaling. The last results in considerable Ti copy number increase and collective elevation of Ti gene expression. Inhibition of the Ti repABC is in turn conferred by a plant defense compound, which primarily affects Agrobacterium virulence and interferes with cell-density perception. Altogether, the above suggest that the entire Ti gene pool is subjected to the bacterium-eukaryote signaling network, a phenomenon quite unprecedented for replicons thought of as stringently controlled. It remains to be seen whether similar copy number variations characterize related replicons or if they are of even broader significance in plasmid biology.
机译：根癌农杆菌致癌Ti质粒通过repABC盒复制并分离到子细胞，其中repA和repB是质粒分配基因，repC编码复制起始蛋白。 repABC盒在越来越多的α-变形杆菌的质粒和染色体中遇到，并且农杆菌，根瘤菌和副球菌的特定代表的发现已开始阐明它们的结构和功能。在repABC复制子中，Ti质粒，尤其是章鱼碱型Ti最近成为调节repABC基础表达的模型，该模型在质粒拷贝数控制中起作用，但似乎在细菌和宿主之间也经历了repABC的明显上调。细菌信号。最后导致大量的Ti拷贝数增加和Ti基因表达的总体升高。 Ti repABC的抑制作用继而由植物防御化合物赋予，该化合物主要影响土壤杆菌的毒力并干扰细胞密度的感知。总而言之，以上表明整个Ti基因库都受到细菌-真核生物信号网络的作用，对于被认为严格控制的复制子而言，这种现象是前所未有的。相似的拷贝数变异是否是相关复制子的特征，或者它们是否在质粒生物学中具有更广泛的意义还有待观察。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号