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Protection(and Deprotection)of Functional Groups in Organic Synthesis by Heterogeneous Catalysis

机译:非均相催化有机合成中官能团的保护(和脱保护)

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Fine chemicals are complex and multifunctional molecules,often characterized by low volatility and limited thermal stability,whose manufacture generally is based on multistep synthesis performed in the liquid phase and frequently involving protection- deprotection steps.The use of blocking functions in organic synthesis,developed for nearly 100 years,makes more complex the entire synthetic plan since it requires at least two additional steps.At the same time,environmental and economic considerations have created interest,in both academic and industrial research,in designing synthetic procedures that are clean,selective,high-yielding,and manipula-tively easy.
机译:精细化学品是复杂且多功能的分子,通常具有挥发性低和热稳定性有限的特点,其制造通常基于在液相中进行的多步合成,并且通常涉及保护-脱保护步骤。近一百年来,由于至少需要两个额外的步骤,因此使整个合成计划变得更加复杂。同时,出于环境和经济方面的考虑,学术和工业研究都对设计清洁,选择性,高收益且操作简便。

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