...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Chemical Senses >Modeling Inspiratory and Expiratory Steady-State Velocity Fields in the Sprague-Dawley Rat Nasal Cavity
【24h】

Modeling Inspiratory and Expiratory Steady-State Velocity Fields in the Sprague-Dawley Rat Nasal Cavity

机译：Sprague-Dawley大鼠鼻腔中吸气和呼气稳态速度场的建模

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Distribution patterns of odorant molecules in the rat nasal olfactory region depend in large part on the detailed airflow patterns in the nasal cavity,which in turn depend on the anatomical structure.To investigate these flow patterns,we constructed an anatomically accurate finite element model of the right nasal cavity of the Sprague-Dawley rat based on horizontal(anterior-posterior)nasal cast cross sections.By numerically solving the fluid mechanical momentum and continuity equations using the finite element method,we studied the flow distribution and the complete velocity field for both inspiration and expiration throughout the nasal cavity under physiological flow rates of resting breathing and sniffing.Detailed velocity profiles,volumetric flow distributions,and streamline patterns for quasi-steady airflow are presented.S-shaped streamlines passing through the olfactory region are found to be less prevalent during expiratory than inspiratory flow leading to trapping and an increase in odorant molecule retention in the olfactory region during sniffing.The rat nasal velocity calculations will be used to study the distribution of odorant uptake onto the rat olfactory mucosa and compare it with the known anatomic location of some types of rat olfactory receptors.
机译：大鼠鼻嗅区域中气味分子的分布模式在很大程度上取决于鼻腔内的详细气流模式，而这又取决于解剖结构。为了研究这些流模式，我们构建了解剖学上精确的有限元模型。基于水平（前后）铸件横截面的Sprague-Dawley大鼠右鼻腔。通过使用有限元方法对流体力学动量和连续性方程进行数值求解，我们研究了两者的流场分布和全速度场在静息呼吸和嗅探的生理流速下，整个鼻腔的吸气和呼气。呈现详细的速度分布，体积流量分布和准稳定气流的流线型式。通过嗅觉区域的S形流线较少呼气时比吸气时多见，导致诱捕和增加嗅嗅过程中气味分子在嗅觉区域中的保留。大鼠鼻腔速度计算将用于研究嗅觉吸收在大鼠嗅粘膜上的分布，并将其与某些类型的大鼠嗅觉受体的已知解剖位置进行比较。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号