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首页> 外文期刊>Postgraduate Medical Journal >Clinical applications and advances of positron emission tomography with fluorine-18-fluorodeoxyglucose (18F-FDG) in the diagnosis of liver neoplasms.
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Clinical applications and advances of positron emission tomography with fluorine-18-fluorodeoxyglucose (18F-FDG) in the diagnosis of liver neoplasms.

机译：氟-18-氟脱氧葡萄糖（18F-FDG）的正电子发射断层扫描在肝肿瘤诊断中的临床应用和进展。

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摘要

Positron emission tomography (PET) using 18F-fluorodeoxyglucose (18F-FDG) has been widely used not only for detecting and staging malignant tumours but also for monitoring therapy response and for differentiating malignant lesions from benign lesions. However, the sensitivity of 18F-FDG PET for hepatocellular carcinoma (HCC) is low. Recent research about the novel drug shows that the sensitivity of 11C-acetate PET for HCC is higher than that of 18F-FDG PET and 11C-acetate also indicates tumour cell differentiation. 18F-FDG PET proved to be highly sensitive in detecting hepatic metastases from different primaries. 18F-FDG PET has also been shown to be useful and more accurate than conventional imaging modalities in demonstrating the effect of local treatments in liver tumours. With the development of small animal imaging, animal research about 18F-FDG PET is increasing.
机译：使用18F-氟脱氧葡萄糖（18F-FDG）的正电子发射断层扫描（PET）已被广泛用于检测和分期恶性肿瘤，还用于监测治疗反应以及区分恶性病变与良性病变。但是，18 F-FDG PET对肝细胞癌（HCC）的敏感性较低。关于该新药的最新研究表明，11C-乙酸PET对HCC的敏感性高于18F-FDG PET，而11C-乙酸也表明肿瘤细胞的分化。事实证明，18F-FDG PET对检测来自不同原发灶的肝转移非常敏感。还证明了18F-FDG PET在证明局部治疗对肝肿瘤的作用方面比传统的成像方法有用且更准确。随着小动物成像技术的发展，有关18F-FDG PET的动物研究也在不断增加。

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