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首页> 外文期刊>Postgraduate Medical Journal >Cytomegalovirus retinitis in patients with acquired immune deficiency syndrome.
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Cytomegalovirus retinitis in patients with acquired immune deficiency syndrome.

机译：获得性免疫缺陷综合征患者的巨细胞病毒性视网膜炎。

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摘要

Cytomegalovirus (CMV) retinitis is the most common intra-ocular infection in patients with acquired immune deficiency syndrome (AIDS), and a leading cause of AIDS-related morbidity. Untreated CMV retinitis in AIDS patients is a progressive and potentially blinding disorder. The diagnosis of CMV retinitis is a clinical one and it is important for physicians to be familiar with the clinical features of the disease. Ophthalmic screening of AIDS sufferers should be undertaken at regular intervals, and this is dictated, in part, by the patient's CD4+ T-lymphocyte (CD4) counts. CMV retinitis may be treated with systemic ganciclovir, foscarnet or cidofovir, or with local (intravitreal) therpy. CMV-related retinal detachment is treated surgically. In some patients with quiescent CMV retinitis receiving highly active anti-retroviral therapy, anti-CMV maintenance therapy may be discontinued in favour of close ophthalmologic observation and CD4 count monitoring.
机译：巨细胞病毒（CMV）视网膜炎是获得性免疫缺陷综合症（AIDS）患者最常见的眼内感染，也是AIDS相关发病率的主要原因。艾滋病患者未经治疗的CMV视网膜炎是一种进行性疾病，可能是致盲性疾病。 CMV视网膜炎的诊断是一种临床诊断，对医生而言，熟悉该疾病的临床特征很重要。应当定期对爱滋病患者进行眼科筛查，这部分取决于患者的CD4 + T淋巴细胞（CD4）计数。巨细胞病毒性视网膜炎可用全身更昔洛韦，膦甲酸或西多福韦或局部（玻璃体内）疗法治疗。与CMV相关的视网膜脱离可通过手术治疗。在某些接受高活性抗逆转录病毒疗法的静止CMV视网膜炎患者中，可能停止使用抗CMV维持疗法，以进行密切的眼科观察和CD4计数监测。

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