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首页> 外文期刊>Prehospital emergency care >Method of cold saline storage for prehospital induced hypothermia.
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Method of cold saline storage for prehospital induced hypothermia.

机译：院前诱发体温过低的冷盐水储存方法。

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OBJECTIVE: Research over the last decade has supported the use of cold intravenous (IV) fluid as a method for initiating therapeutic hypothermia in post-cardiac arrest resuscitation. However, prehospital care programs employing this treatment have encountered various difficulties. Barriers to prehospital induced hypothermia (IH) protocols include the lack of effective or economically reasonable methods to maintain cold saline in the field. Validation of a simple method could allow agencies to equip numerous rigs with cold saline. The aim of this study was to determine whether a standard commercial cooler can maintain two 1-L normal saline solution (NSS) bags below 4 degrees C in three different environments. METHODS: Environments simulating those of an ambulance compartment were created for the experiment. NSS temperatures were continuously recorded inside a standard commercial cooler under one of three scenarios: ambient room temperature (25 degrees C) without ice packs, ambient room temperature with ice packs, and 50 degrees C ambient temperature with ice packs. Four trials under each condition were performed. RESULTS: In a room-temperature environment without ice packs, the NSS warmed to 4 degrees C in a mean interval of 1 hour 21 minutes. Using room temperature with ice packs, the NSS warmed to 4 degrees C in a mean interval of 29 hours 53 minutes. In a constant hot environment of 50 degrees C, the NSS warmed to 4 degrees C in a mean interval of 10 hours 50 minutes. A significant difference was found between the three environments (log-rank = 17.90, df = 2, p = 0.0001). CONCLUSIONS: Prehospital refrigeration devices are needed for current and future IH protocols. Low-technology methods in the form of a cooler and ice packs can provide cold saline storage for longer than a full 24-hour shift in a room-temperature ambulance. In extremely hot conditions, 4 degrees C NSS can be maintained for nearly 11 hours using this method. This model exhibits an economical, easily deployable cold saline storage unit.
机译：目的：近十年来的研究支持在心脏骤停后复苏中使用冷静脉注射液作为引发治疗性体温过低的方法。然而，采用这种治疗的院前护理方案遇到了各种困难。院前诱导的体温过低（IH）方案的障碍包括缺乏有效或经济上合理的方法来在现场维持冷盐水。一种简单方法的验证可以使代理商为大量钻机配备冷盐水。这项研究的目的是确定标准的商用冷却器是否可以在三种不同的环境中将两个1-L生理盐水溶液（NSS）袋保持在4摄氏度以下。方法：为实验创建了模拟救护车厢环境的环境。在以下三种情况之一下，在标准商用冷却器内连续记录NSS温度：无冰袋的室温（25摄氏度），有冰袋的室温和有冰袋的50摄氏度。在每种条件下进行了四次试验。结果：在没有冰袋的室温环境中，NSS平均以1小时21分钟的间隔升至4摄氏度。在装有冰袋的室温下，NSS平均以29小时53分钟的间隔升至4摄氏度。在50摄氏度的恒定高温环境中，NSS平均以10小时50分钟的间隔升至4摄氏度。发现这三种环境之间存在显着差异（对数秩= 17.90，df = 2，p = 0.0001）。结论：当前和未来的IH方案需要院前制冷设备。冷藏箱和冰袋形式的低技术方法可以提供比室温救护车整整24小时更长时间的冷盐水储存。在极热的条件下，使用此方法可以将4摄氏度的NSS维持近11小时。该模型展示了一种经济，易于部署的冷盐水存储单元。

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