Platelet to lymphocyte ratio as a prognostic marker in primary percutaneous coronary intervention

Ayca Burak; Akin Fatih; Celik Omer; Yuksel Yasin; Ozturk Derya; Tekiner Fatih; Cetin Sukru; Okuyan Ertugrul; Dinckal Hakan

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Platelet to lymphocyte ratio as a prognostic marker in primary percutaneous coronary intervention

机译：血小板与淋巴细胞之比作为原发性经皮冠状动脉介入治疗的预后指标

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We assessed the prognostic value of the platelet to lymphocyte ratio (PLR) in primary percutaneous coronary intervention (pPCI). Patients (n = 440) with acute myocardial infarction (AMI) who underwent pPCI were divided into 2 groups: low PLR (5137) and high PLR (4137). "Thrombolysis In Myocardial Infarction'' (TIMI) flow grades and Syntax scores (SXS) were calculated from initial angiograms. In-hospital mortality rate and cardiac adverse events were obtained from medical records. Patients with high PLR had more no-reflow, higher SXS and higher mortality rate (p<0.001, p<0.001 and p = 0.008, respectively). In receiver operating characteristic curve analysis, high PLR predicted development of no-reflow (specificity 71% and sensitivity 85%), SXS422 (specificity 52% and sensitivity 61%) and adverse events (specificity 67% and sensitivity 63%). In multivariate regression analysis, PLR was an independent risk factor for no-reflow, SXS422 and in-hospital adverse events. In addition to PLR, we present the relationship between mean platelet volume, red cell distribution width and neutrophil to lymphocyte ratio and no-reflow, SXS and in-hospital adverse events.

机译：我们评估了血小板/淋巴细胞比率（PLR）在原发性经皮冠状动脉介入治疗（pPCI）中的预后价值。接受pPCI的急性心肌梗死（AMI）患者（n = 440）分为两组：低PLR（5137）和高PLR（4137）。从初始血管造影中计算出“心肌梗塞溶栓”（TIMI）血流等级和语法评分（SXS），从医疗记录中获得院内死亡率和心脏不良事件，PLR较高的患者无复流率更高， SXS和较高的死亡率（分别为p <0.001，p <0.001和p = 0.008）在接收器工作特性曲线分析中，高PLR预测无回流（特异性71％，灵敏度85％），SXS422（特异性52）的发展％和敏感性61％）和不良事件（特异性67％和敏感性63％）。在多因素回归分析中，PLR是无复流，SXS422和医院内不良事件的独立危险因素。血小板平均体积，红细胞分布宽度和嗜中性白细胞与淋巴细胞的比率与无复流，SXS和医院内不良事件之间的关系。

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《Platelets》 |2015年第7期|共7页
作者
Ayca Burak; Akin Fatih; Celik Omer; Yuksel Yasin; Ozturk Derya; Tekiner Fatih; Cetin Sukru; Okuyan Ertugrul; Dinckal Hakan;
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中图分类基础医学;
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Mortality; no-reflow; platelet to lymphocyte ratio; primary percutaneous coronary intervention; syntax score;

机译：死亡率;不复流;血小板与淋巴细胞比率;一次经皮冠状动脉介入治疗;语法评分;

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1. Platelet to lymphocyte ratio as a prognostic marker in primary percutaneous coronary intervention [J] . Ayca Burak, Akin Fatih, Celik Omer, Platelets . 2015,第7期

机译：血小板与淋巴细胞之比作为原发性经皮冠状动脉介入治疗的预后指标
2. Neutrophil-Lymphocyte Ratio and Platelet-Lymphocyte Ratio Combination Can Predict Prognosis in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention [J] . Cicek Gokhan, Acikgoz Sadik Kadri, Bozbay Mehmet, Angiology: the Journal of Vascular Diseases . 2015,第5期

机译：中性粒细胞-淋巴细胞比和血小板-淋巴细胞比的组合可以预测ST段抬高型心肌梗死患者行经皮冠状动脉介入治疗的预后
3. Value of combination of the neutrophil to lymphocyte ratio and platelet to lymphocyte ratio in primary percutaneous coronary intervention [J] . Sertoglu Erdim, Uyanik Metin Platelets . 2015,第8期

机译：中性粒细胞与淋巴细胞比例和血小板与淋巴细胞比例的组合在初次经皮冠状动脉介入治疗中的价值
4. Predicting 30 days Mortality in STEMI Patients using Patient Referral Data to a Primary Percutaneous Coronary Intervention Service [C] . Aleeha Iftikhar, Raymond Bond, Victoria McGilligan, IEEE International Conference on Bioinformatics and Biomedicine . 2019

机译：使用患者转诊至主要经皮冠状动脉介入治疗服务的数据来预测STEMI患者的30天死亡率
5. The lived experience of heart attack: Individual accounts of primary percutaneous coronary intervention survivors [D] . Laberge, Carol G. 2012

机译：心脏病发作的实际经验：主要经皮冠状动脉介入治疗幸存者的个人资料
6. Prognostic utility of the combination of monocyte-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio in patients with NSTEMI after primary percutaneous coronary intervention: a retrospective cohort study [O] . Zeyuan Fan, Yang Li, Hanhua Ji, 2018

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Platelet to lymphocyte ratio as a prognostic marker in primary percutaneous coronary intervention

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