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首页> 外文期刊>Prescrire international >Secondary leukaemia: After umbilical cord blood stem cell transplantation too
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Secondary leukaemia: After umbilical cord blood stem cell transplantation too

机译：继发性白血病：脐血干细胞移植后

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摘要

? Since the late 1990s, umbilical cord blood stem cells have been used to treat some severe haematological disorders. In theory, this type of transplant carries a lower risk of immunological incompatibility. ? Ten cases of secondary leukaemia following cord blood stem cell transplantation have been published in detail, including 7 cases of acute myeloid leukaemia. The malignancies were diagnosed between 5 and 40 months after transplantation. The patients were severely immunodepressed, and analysis showed that the leukaemias were of donor cell origin. ? Patients receiving cord blood stem cell grafts, like all transplant recipients, should therefore be monitored for secondary leukaemia.
机译：？自1990年代后期以来，脐带血干细胞已被用于治疗一些严重的血液病。从理论上讲，这种类型的移植具有较低的免疫学不相容性风险。 ？已详细发表了10例脐带血干细胞移植后继发性白血病的病例，其中包括7例急性髓样白血病。移植后5至40个月诊断为恶性肿瘤。患者被严重免疫抑制，分析表明白血病是供体细胞起源的。 ？因此，与所有移植受者一样，接受脐带血干细胞移植的患者应进行继发性白血病的监测。

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