Hydroxycarbamide in sickle cell syndrome: new drug. For severe cases only.

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Hydroxycarbamide in sickle cell syndrome: new drug. For severe cases only.

机译：镰状细胞综合征中的羟脲：新药。仅适用于严重情况。

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Patients with sickle-cell syndrome suffer from chronic haemolytic anaemia and unpredictable painful vaso-occlusive crises. The resulting vascular ischaemia can lead to necroses. The acute chest syndrome is a severe pulmonary form of these attacks. The underlying cause of sickle-cell syndrome is a genetic mutation. There is no curative treatment.

机译：镰状细胞综合征患者患有慢性溶血性贫血和无法预测的痛苦性血管闭塞性危机。由此产生的血管缺血可导致坏死。急性胸综合症是这些发作的严重肺部形式。镰状细胞综合征的根本原因是遗传突变。没有治疗方法。

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《Prescrire international》 |2009年第99期|共1页
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正文语种 eng
中图分类药学;
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1. Hydroxycarbamide in sickle cell syndrome: new drug. For severe cases only. [J] . Prescrire international . 2009,第99期

机译：镰状细胞综合征中的羟脲：新药。仅适用于严重情况。
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3. Effectiveness of hydroxycarbamide in children with sickle cell disease – Analysis of dose‐response metrics in a large birth cohort in a tertiary sickle cell centre [J] . Park Hyun, Bhatti Sabah, Chakravorty Subarna Pediatric blood & cancer . 2019,第7期

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4. Small molecules blocking the entry of severe acute respiratory syndrome coronavirus into host cells [C] . 北京大学中医药现代研究中心2004年年会论文集 . 2005

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5. Age and perceived self-efficacy in the use of self-hypnosis to manage severe pain in children, adolescents, and adults with sickle cell disease [D] . Bauer, Nancy K. 1998

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6. Differential modulation of adhesion molecule expression by hydroxycarbamide in human endothelial cells from the micro- and macrocirculation: potential implications in sickle cell disease vasoocclusive events [O] . Sandrine Laurance, Pauline Lansiaux, François-Xavier Pellay, 2011

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7. Inheritance of the Bantu/Benin haplotype causes less severe hemolytic and oxidative stress in sickle cell anemia patients treated with hydroxycarbamide [O] . Jéssika V Okumura, Danilo G H Silva, Lidiane S Torres, 2016

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Hydroxycarbamide in sickle cell syndrome: new drug. For severe cases only.

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