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Antibiotics and asthma in children.

机译:儿童抗生素和哮喘。

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摘要

(1) A longitudinal cohort study showed an increase in the frequency of asthma among 7-year-old children who were treated with antibiotics during the first year of life, even when treatment was for non-respiratory tract infections. The risk increased with the number of antibiotic courses with the use of broad-spectrum antibiotics; (2) A meta-analysis of epidemiological studies showed that the risk of asthma doubled when antibiotics were administered during the first year of life. No such link was found in the combined analysis of the few existing prospective studies; (3) In practice, the likely benefits and risks should be carefully weighed before prescribing an antibiotic to a child. A narrow-spectrum antibiotic should be chosen whenever possible.
机译:(1)一项纵向队列研究显示,即使是非呼吸道感染治疗,在生命的第一年内接受抗生素治疗的7岁儿童中哮喘的发病率也会增加。随着使用广谱抗生素的抗生素疗程数的增加,风险增加; (2)一项流行病学研究的荟萃分析显示,在生命的第一年使用抗生素时,哮喘的风险增加了一倍。在对一些现有的前瞻性研究的综合分析中没有发现这样的联系。 (3)实际上,在给孩子服用抗生素之前,应仔细权衡可能的收益和风险。应尽可能选择窄谱抗生素。

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    《Prescrire international》 |2009年第103期|共1页
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  • 正文语种 eng
  • 中图分类 药学;
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