Iosartan and hypertensive children: Another option for a small number of children

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Iosartan and hypertensive children: Another option for a small number of children

机译：氯沙坦和高血压儿童：少数儿童的另一种选择

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Losartan (Cozaar, MSD-Chibret) is the first angiotensin II receptor blocker (ARB) to be authorised in this setting, although no oral solution was available in France as of 3 March 2010 (1,2). Clinical evaluation is based on a dose-ranging study in 177 children, aged 6 to 16 years, without severe renal impairment. Overall, the hypotensive effect was dose-dependent (1,3).The adverse effect profile appeared to be similar to that seen in adults (1).

机译：Losartan（Cozaar，MSD-Chibret）是第一种在这种情况下获准使用的血管紧张素II受体阻滞剂（ARB），尽管截至2010年3月3日法国尚无口服溶液（1,2）。临床评估基于对177名6至16岁，无严重肾功能不全儿童的剂量范围研究。总体而言，降压作用是剂量依赖性的（1,3）。不良反应特征似乎与成年人相似（1）。

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《Prescrire international》 |2010年第108期|共1页
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中图分类药学;
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机译：氯沙坦和高血压儿童：少数儿童的另一种选择
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Iosartan and hypertensive children: Another option for a small number of children

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