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首页> 外文期刊>Preventive Medicine: An International Journal Devoted to Practice and Theory >Relationship between birth weight and blood pressure in adolescence.
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Relationship between birth weight and blood pressure in adolescence.

机译：出生体重与青春期血压之间的关系。

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摘要

BACKGROUND: Several studies have found a relation ship between small size at birth and high blood pressure (HBP). However, this association has not been fully evaluated in adolescence. The aim of the present study was to evaluate the relation of birth weight (BW) to BP in adolescence, controlling for factors related to BP, to extrauterine environment, and to maternal risk of fetal distress. METHODS: In 1310 adolescents (ages 12-14 years), randomly selected from Turin school children, we evaluated BP, heart rate (HR), weight, height, familial risk of hypertension, parental cultural level, BW, and maternal history of diseases during pregnancy. The BW-BP association was tested by using multiple regression analysis and adjusting for the other variables mentioned above. The same analysis was done for the subgroup at high risk of fetal distress. RESULTS: The association between BW and BP was negative but weak when we adjusted for all confounders (= -0.07 in males; = -0.27 in females). The association was negative and became stronger after the inclusion of all confounders, particularly HR (= -3.92), in the group of children at high risk of fetal distress. CONCLUSIONS: Intrauterine environment, as reflected by BW, has little effect on BP in early adolescence without concomitant maternal diseases or environmental conditions leading to severe placental hypoperfusion. Copyright 1999 American Health Foundation and Academic Press.
机译：背景：几项研究发现出生时体重过小与高血压（HBP）之间存在关系。但是，这种关联尚未在青春期得到充分评估。本研究的目的是评估青春期出生体重（BW）与BP的关系，控制与BP相关的因素，宫外环境以及产妇的胎儿窘迫风险。方法：从都灵学校的儿童中随机选择的1310名青少年（12-14岁）中，我们评估了BP，心率（HR），体重，身高，家族性高血压风险，父母的文化水平，体重和母亲的病史在怀孕期间。通过使用多元回归分析并调整上述其他变量来测试BW-BP关联。对胎儿窘迫高危人群进行了相同的分析。结果：当我们对所有混杂因素进行校正后，体重与血压之间的关联为负，但较弱（男性= -0.07;女性= -0.27）。在将所有混杂因素，特别是HR（= -3.92）包括在胎儿窘迫高危儿童组中之后，这种关联是消极的，并且变得更强。结论：BW反映的宫腔环境在青春期早期对BP几乎没有影响，没有伴随的母体疾病或环境条件导致严重的胎盘灌注不足。版权所有1999美国健康基金会和学术出版社。

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