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首页> 外文期刊>Preventive Medicine: An International Journal Devoted to Practice and Theory >Do too many shots due lead to missed vaccination opportunities? Does it matter?
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Do too many shots due lead to missed vaccination opportunities? Does it matter?

机译：注射过多会导致错过疫苗接种机会吗？有关系吗？

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BACKGROUND: Missed childhood vaccination opportunities have been generally described, yet not since the immunization schedule's recent rapid expansion. Little is known about the relationship between the number of vaccine doses due and whether all scheduled doses are administered, and the effect of dose deferral on immunization coverage. METHODS: 32 private pediatrics centers reviewed medical records covering the first 2 years of life for 858 patients. For each visit during ages 2-8 months, we determined the numbers of vaccine doses due versus administered. Logistic regression was used to assess the effect of dose deferral on immunization coverage at ages 1 and 2 years. RESULTS: Of 2224 visits during ages 2-8 months at which > or =1 dose was administered, > or =1 due dose was deferred at 26%, 34%, and 48% of the visits at which < or =3, 4, and 5 doses were due, respectively. Absence of a deferred dose visit predicted increased coverage at age 1 (adjusted odds ratio: 2.4, 95% confidence interval: 1.8-3.2) and 2 years (2.1, 1.4-3.0). CONCLUSIONS: Administering some but not all vaccine doses at visits during ages 2-8 months impairs immunization coverage through age 2 years.
机译：背景：总体上已经描述了儿童期错过的疫苗接种机会，但是自从免疫计划最近迅速扩展以来，还没有。关于到期的疫苗剂量数量与是否已计划所有预定剂量之间的关系以及剂量延期对免疫覆盖率的影响知之甚少。方法：32个私人儿科中心审查了858例患者生命最初2年的病历。对于2-8个月大的每次访问，我们确定了应接种疫苗数量与已接种疫苗的数量。 Logistic回归用于评估剂量延迟对1岁和2岁儿童免疫覆盖率的影响。结果：在2-8个月的2224次就诊中，给予>或= 1剂量，而>或= 1适当剂量被推迟到分别为<或= 3、4的就诊中分别占26％，34％和48％ ，分别是5剂。如果没有推迟剂量就诊，则预计在1岁时（调整后的优势比：2.4，95％置信区间：1.8-3.2）和2年（2.1、1.4-3.0）时，覆盖率会增加。结论：在2-8个月大的访问期间施用部分而非全部疫苗剂量会损害到2岁的免疫覆盖率。

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