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Dyslipidemia in Shanghai, China.

机译:中国上海血脂异常。

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OBJECTIVES: To determine the prevalence of and risk factors for dyslipidemia in Shanghai. METHODS: A cross-sectional survey of 14,385 subjects (6150 men) with mean age of 49.5 (14.5) years was conducted between October 2002 and April 2003 using randomized, stratified cluster sampling. Serum triglyceride, total cholesterol (TC) and high-density lipoprotein cholesterol (HDL-C) were measured. RESULTS: Dyslipidemia, as defined by NCEP ATP III criteria, occurred in 5255 subjects (36.5%). The prevalences of mixed hyperlipidemia (elevated TC and triglycerides), isolated hypertriglyceridemia, isolated hypercholesterolemia and isolated low HDL-C were 3.8%, 24.9%, 3.2% and 4.7%, respectively. The prevalence of dyslipidemia increased with age, with the peak prevalence (43%) occurring after age 55. Dyslipidemia was more common in males than females (40.2% vs. 33.8%) and in rural than urban populations (44.2% vs. 32.3%). Serum triglyceride and TC increased with body mass index (BMI) and waist circumference. Mean serum triglyceride concentrations in males and rural residents were higher than those in females and urban residents, respectively, whereas the reverse was true for HDL-C values. Multivariate analysis revealed that dyslipidemia was associated with age, gender, area of residence, BMI and waist circumference. CONCLUSIONS: There is a high prevalence of dyslipidemia, mainly hypertriglyceridemia and low HDL-C, in Shanghai.
机译:目的:确定上海市血脂异常的患病率和危险因素。方法:采用随机分层整群抽样方法,于2002年10月至2003年4月之间对14385名受试者(6150名男性)进行了横断面调查,平均年龄为49.5(14.5)岁。测量血清甘油三酸酯,总胆固醇(TC)和高密度脂蛋白胆固醇(HDL-C)。结果:NCEP ATP III标准定义的血脂异常发生在5255名受试者中(36.5%)。混合性高脂血症(TC和甘油三酯升高),孤立的高甘油三酯血症,孤立的高胆固醇血症和孤立的低HDL-C的患病率分别为3.8%,24.9%,3.2%和4.7%。血脂异常的患病率随年龄增长而增加,最高发病率(43%)发生在55岁以后。男性中血脂异常的发生率高于女性(40.2%对33.8%),农村地区比城市人群高(44.2%对32.3%) )。血清甘油三酸酯和TC随着体重指数(BMI)和腰围的增加而增加。男性和农村居民的平均血清甘油三酸酯浓度分别高于女性和城市居民,而HDL-C值则相反。多因素分析表明,血脂异常与年龄,性别,居住面积,BMI和腰围有关。结论:上海的血脂异常患病率较高,主要是高甘油三酯血症和低HDL-C。

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