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首页> 外文期刊>Preventive Medicine: An International Journal Devoted to Practice and Theory >Ecological analysis of the relationship between infant mortality and cardiovascular disease mortality at ages 45-69 in the Brazilian 1935 birth cohort.
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Ecological analysis of the relationship between infant mortality and cardiovascular disease mortality at ages 45-69 in the Brazilian 1935 birth cohort.

机译：巴西1935年出生队列中45-69岁年龄段婴儿死亡率与心血管疾病死亡率之间关系的生态分析。

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BACKGROUND: International ecological studies have shown a positive association between infant mortality as a proxy for low birth weight and cardiovascular disease mortality in adult life. METHODS: Mortality rates due to Cardiovascular Diseases (CVDMR) standardised by age in adults between 45 and 69 years of age and by place of birth (pob) and residence (res) were related to Infant Mortality Rates (IMR) in the Brazilian 1935 birth cohort. RESULTS: Two relationship patterns were noted between IMR and CVDMR: for the Southeast, South and Centre-West group of regions (r(pob)=0.46; r(res)=0.29) and for the North and Northeast group of regions (r(pob)=0.21; r(res)=0.33). For the latter pattern, two states were identified (Rio Grande do Norte and Paraiba) as atypical areas, whose exclusion strengthened the association (r(pob)=0.73; r(res)=0.91). CONCLUSIONS: The direction of the associations changed after the analysis by group of Brazilian regions (indirect control of socio-economic levels, coverage and quality of the information). There is a positive, although weak association between IMR and CVDMR. Attempts to control or minimise the interference of migratory movements, cohort effects and socio-economic levels represented methodological progress in ecological analyses of foetal programming in Brazil.
机译：背景：国际生态学研究表明，低出生体重的婴儿死亡率与成年后心血管疾病死亡率之间存在正相关关系。方法：按年龄对45岁至69岁之间的成年人以及出生地（pob）和居住地（res）标准化的心血管疾病（CVDMR）死亡率与1935年巴西出生的婴儿死亡率（IMR）相关队列。结果：IMR和CVDMR之间注意到两个关系模式：东南，南部和中西部地区（r（pob）= 0.46; r（res）= 0.29）和北部和东北地区（r （pob）＝ 0.21; r（res）＝ 0.33）。对于后一种模式，确定了两个州（Rio Grande do Norte和Paraiba）为非典型区域，其排除加强了关联（r（pob）= 0.73; r（res）= 0.91）。结论：按巴西地区分组进行分析后，协会的方向发生了变化（间接控制社会经济水平，信息的覆盖范围和质量）。尽管IMR和CVDMR之间存在弱的正相关关系。试图控制或最大程度地减少迁徙活动，队列效应和社会经济水平的干扰，代表了巴西胎儿计划的生态学分析方法学的进步。

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