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首页> 外文期刊>Preventive Medicine: An International Journal Devoted to Practice and Theory >Leisure-time physical activity and breast cancer risk defined by estrogen and progesterone receptor status--the Japan Public Health Center-based Prospective Study.
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Leisure-time physical activity and breast cancer risk defined by estrogen and progesterone receptor status--the Japan Public Health Center-based Prospective Study.

机译：由雌激素和孕激素受体状态定义的休闲运动和乳腺癌风险-基于日本公共卫生中心的前瞻性研究。

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OBJECTIVE: The study aims to investigate the association between leisure-time physical activity and breast cancer risk in consideration of tumor estrogen-receptor/progesterone-receptor status. METHODS: We conducted a population-based prospective cohort study among 53,578 women in the Japan Public Health Center-based Prospective Study. Leisure-time physical activity was assessed by self-reported questionnaires. A Cox proportional hazards regression model was used to derive relative risks and 95% confidence intervals. RESULTS: From 1990-1993 to the end of 2007, 652 cases were identified. The breast cancer rates (per 100,000 person-years) in the sedentary groups (/=3 days/week vs. /=25 kg/m(2) group, leisure-time physical activity was associated with decreased risk (relative risk(>/=1 day/week vs.
机译：目的：本研究旨在考虑肿瘤雌激素受体/孕激素受体状态，探讨休闲运动与乳腺癌风险之间的关系。方法：我们在基于日本公共卫生中心的前瞻性研究中对53578名女性进行了基于人群的前瞻性队列研究。闲暇时间的体育活动通过自我报告的问卷进行评估。使用Cox比例风险回归模型得出相对风险和95％置信区间。结果：从1990年至1993年至2007年底，共确诊652例。久坐组（每3个月/月）的乳腺癌患病率（每100,000人年）为84，绝经前妇女为97，绝经后妇女为75。我们观察到休闲时间体育锻炼与乳腺癌风险之间存在统计学上的显着负相关关系（相对风险（> / = 3天/周与 / = 25 kg / m（2）组中，休闲时间的体育锻炼与降低的风险相关（相对风险（> / = 1天/周与

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