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首页> 外文期刊>Preventive Medicine: An International Journal Devoted to Practice and Theory >Participation in health check-ups and mortality using propensity score matched cohort analyses.
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Participation in health check-ups and mortality using propensity score matched cohort analyses.

机译：使用倾向得分匹配的队列分析参加健康检查和死亡率。

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OBJECTIVE: All Japanese aged >/=40 years are eligible for free annual health check-ups including blood pressure and cholesterol measurements. It is well known that health check-up screenees are more likely to have healthy lifestyles and better health conditions than non-screenees. Therefore, controlling these factors is required to investigate whether screenees have a lower mortality risk than non-screenees independent of their lifestyles or health conditions. METHODS: We followed 48,775 Japanese National Health Insurance beneficiaries aged 40-79 years since 1994 for 11 years. We used Cox proportional hazard models adjusted for possible confounding factors. We also performed propensity for use of the health check-up matched cohort analyses. RESULTS: Compared to non-screenees, multiple-adjusted hazard ratios (95% confidence intervals) for all-cause and cardiovascular disease mortality among screenees were 0.74 (0.62-0.88) and 0.65 (0.44-0.95) for men and 0.69 (0.52-0.91) and 0.61 (0.36-1.04) for women, respectively. These relations were also observed when we used propensity matched cohort analyses. CONCLUSION: This is the first study to show that mortality rates are lower among screenees than non-screenees in Japanese health check-ups when propensity matched cohort analyses were used for adjusting confounding factors. Further prospective studies, including randomized controlled trials, are required to confirm whether screening lowers mortality.
机译：目的：所有年龄在40岁以上的日本人都可以免费进行年度健康检查，包括血压和胆固醇测量。众所周知，健康检查的受检者比非受检者更有可能拥有健康的生活方式和更好的健康状况。因此，需要控制这些因素以调查受筛查者的死亡率风险是否比不受筛查者高，而不受其生活方式或健康状况的影响。方法：自1994年以来，我们追踪了48,775名年龄在40-79岁的日本国民健康保险受益人，为期11年。我们使用了针对可能的混杂因素进行调整的Cox比例风险模型。我们还进行了使用健康检查匹配的队列分析的倾向。结果：与非筛查者相比，筛查者全因和心血管疾病死亡率的多重调整风险比（95％置信区间）分别为男性的0.74（0.62-0.88）和0.65（0.44-0.95），以及0.69（0.52-）女性分别为0.91和0.61（0.36-1.04）。当我们使用倾向匹配的队列分析时，也观察到了这些关系。结论：这是第一项研究，表明当使用倾向匹配的队列分析来调整混杂因素时，在日本健康检查中，被筛查者的死亡率要低于未筛查者。需要进一步的前瞻性研究，包括随机对照试验，以确认筛查是否可以降低死亡率。

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