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Alcohol use and death from respiratory disease in a prospective Chinese elderly cohort study in Hong Kong

机译:在香港进行的一项前瞻性中国老年人队列研究中,饮酒与呼吸系统疾病致死

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Objective: In Western settings, moderate drinking is negatively associated with respiratory disease. However, moderate drinking is socially patterned, making this association vulnerable to contextual biases. Evidence from other contexts where the typical drinking pattern is different may clarify such observations. Methods: Multivariable Cox regression analysis was used to assess the adjusted associations of alcohol use with death from respiratory disease using a population-based prospective cohort of 66,820 Chinese aged ≥ 65. years enrolled from July 1998 to December 2001 at all the 18 Elderly Health Centers of the Hong Kong Government Department of Health and followed till May 30, 2012. Results: During ten-year follow-up, 4065 deaths from respiratory disease occurred. Most current drinkers were occasional drinkers (< 1. day/week). Both moderate and occasional drinking (< 1. day/week) were associated with a lower risk of death from respiratory disease, but the point estimates and pattern of associations were similar between these two types of drinkers. Conclusion: The typical drinking pattern, i.e. occasional drinking (< 1. day/week), which is unlikely to have any biological effect, was similarly associated with a lower risk of respiratory disease as moderate alcohol use, suggesting the attributes of being a typical drinker may be protective.
机译:目的:在西方国家,适度饮酒与呼吸系统疾病负相关。但是,适度饮酒是社交行为的模式,使这种联想容易受到情境偏见的影响。来自其他饮水模式不同的其他情况的证据可能会澄清此类观察。方法:采用多变量Cox回归分析,以1998年7月至2001年12月在所有18个老年健康中心登记的66,820名年龄≥65岁的中国人为研究对象,评估饮酒与呼吸系统疾病致死的校正关联。随访至2012年5月30日。结果:在十年的随访中,发生了4065例呼吸系统疾病死亡。当前大多数饮酒者为偶尔饮酒者(<1.天/周)。中度饮酒和偶尔饮酒(<1.天/周)与呼吸系统疾病致死的风险降低相关,但两种饮酒者的饮酒量估计和关联模式相似。结论:典型的饮酒模式,即偶尔饮酒(<1.天/周),不太可能具有任何生物学影响,与酒精中度饮酒类似地降低了呼吸道疾病的风险,这表明典型饮酒的特征饮酒者可能具有保护作用。

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