...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Preventive Medicine: An International Journal Devoted to Practice and Theory >Could a federal program to promote influenza vaccination among elders be cost-effective?
【24h】

Could a federal program to promote influenza vaccination among elders be cost-effective?

机译：一项在老年人中促进流感疫苗接种的联邦计划是否具有成本效益？

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

BACKGROUND: Influenza-related mortality predominately and disproportionately impacts the elderly. Rates of annual influenza vaccination among the elderly are approximately 65%, far below the Healthy People 2010 target of 90%. We estimated the cost-effectiveness of a 10-year federal program to promote influenza vaccine, intended to increase vaccination rates among persons > or = 65 years old. METHODS: Published estimates regarding influenza-associated mortality rates and vaccine efficacy among the US elderly were used to calculate the number needed to vaccinate (NNV) to prevent one all-cause death due to influenza, as well as the mortality reduction expected from increased vaccination rates. The costs per life-year saved were estimated for a hypothetical federal promotional campaign, patterned after a direct-to-consumer (DTC) advertising program (2006-2015). The base case scenario presumed a 25-percentage-point increase in vaccination rates to 90%; in sensitivity analyses, we examined programs that increased rates by 10-20 points. RESULTS: The base case NNV was 1116 (95% CI: 993-1348). Over the 10-year DTC-style influenza vaccine promotion program, 6516 (5576-7435) elderly lives would be saved. The incremental cost-effectiveness (C/E) of the program was dollar 16,300 (dollar 11,347-dollar 25,174) per life-year saved in 2006 and increased to dollar 199,906 (dollar 138,613-dollar 307,423) per life-year saved by 2015. Overall, the C/E for the 10-year program was dollar 37,621 (dollar 32,644-dollar 43,939) per life-year saved. Programs that yielded a 15-percentage-point increase or less in vaccination rates would have C/E values exceeding dollar 50,000 per life-year saved and save fewer than 4000 total lives. CONCLUSIONS: DTC-style promotional campaigns for influenza vaccine among elders may represent a cost-effective strategy for the federal government to pursue as a means of increasing elders' vaccination rates and reducing influenza-related mortality.
机译：背景：与流感相关的死亡率主要且不成比例地影响老年人。老年人的年度流感疫苗接种率约为65％，远低于《健康人士2010年》设定的90％的目标。我们估计了一项为期十年的联邦计划以推广流感疫苗的成本效益，该计划旨在提高>或= 65岁人群的疫苗接种率。方法：使用已公布的有关美国老年人中与流感相关的死亡率和疫苗功效的估计值，来计算预防一次流感导致的全因死亡所需的疫苗接种（NNV）数量，以及接种疫苗后预期的死亡率降低费率。假设的联邦促销活动是根据直接面向消费者（DTC）的广告计划（2006-2015）进行的，估算了每个生命年节省的成本。在基本情况下，假定疫苗接种率提高了25个百分点，达到90％;在敏感性分析中，我们检查了将速度提高10-20点的程序。结果：基本案例NNV为1116（95％CI：993-1348）。在为期10年的DTC式流感疫苗推广计划中，将挽救6516（5576-7435）位老年人的生命。该计划的成本效益增量（C / E）为2006年每生命年节省16,300美元（11,347美元至25,174美元），到2015年增加至每生命年199,906美元（138,613美元至307,423美元）。总体而言，该10年计划的C / E为每个生命年节省37,621美元（32,644美元– 43,939美元）。疫苗接种率提高15％或更低的计划，每生命年可节省的C / E值超过50,000美元，并且可挽救少于4000条生命。结论：DTC式的针对老年人的流感疫苗促销活动可能代表联邦政府采取的一种具有成本效益的策略，以此作为提高老年人的疫苗接种率和降低与流感相关的死亡率的手段。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号