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Neural correlates of pediatric obesity.

机译:小儿肥胖的神经相关。

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OBJECTIVE: Childhood obesity rates have increased over the last 40 years and have a detrimental impact on public health. While the causes of the obesity epidemic are complex, obesity ultimately arises from chronic imbalances between energy intake and expenditure. An emerging area of research in obesity has focused on the role of the brain in evaluating the rewarding properties of food and making decisions about what and how much to eat. METHOD: This article reviews recent scientific literature regarding the brain's role in pediatric food motivation and childhood obesity. RESULTS: The article will begin by reviewing some of the recent literature discussing challenges associated with neuroimaging in children and the relevant developmental brain changes that occur in childhood and adolescence. The article will then review studies regarding neural mechanisms of food motivation and the ability to delay gratification in children and how these responses differ in obese compared to healthy weight children. CONCLUSION: Increasing our understanding about how brain function and behavior may differ in children will inform future research, obesity prevention, and interventions targeting childhood obesity.
机译:目的:儿童肥胖率在过去40年中有所增加,并且对公共卫生产生不利影响。尽管肥胖病流行的原因很复杂,但肥胖症最终还是源于能量摄入和支出之间的长期不平衡。肥胖症研究的一个新兴领域集中在大脑在评估食物的有益特性以及决定吃什么和吃多少方面的作用。方法:本文回顾了有关大脑在儿科饮食动机和儿童肥胖中作用的最新科学文献。结果:本文将首先回顾一些最近的文献,这些文献讨论了与儿童神经成像相关的挑战以及在儿童和青少年时期发生的相关发育性大脑变化。然后,本文将回顾有关食物动机的神经机制和延迟满足儿童的能力的研究,以及与健康体重的儿童相比,肥胖中这些反应的差异。结论:加深我们对儿童大脑功能和行为的差异的了解将为将来的研究,预防肥胖和针对儿童肥胖的干预措施提供信息。

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