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首页> 外文期刊>Preventive Medicine: An International Journal Devoted to Practice and Theory >Deciding about prophylactic oophorectomy: what is important to women at increased risk of ovarian cancer?
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Deciding about prophylactic oophorectomy: what is important to women at increased risk of ovarian cancer?

机译：确定预防性卵巢切除术：对于卵巢癌风险增加的女性，重要的是什么？

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BACKGROUND: Little is known about the factors that women at increased risk of ovarian cancer consider to be important when deciding about prophylactic oophorectomy, surgery to remove the ovaries before they develop cancer. METHODS: Women who had undergone prophylactic oophorectomy (surgical group; n = 30) were compared with women who remained on the ovarian screening program (nonsurgical group; n = 28) on their importance ratings for a number of relevant decision-making factors. RESULTS: The most important decision-making factor across all subjects was reducing risk of ovarian cancer, but the single best predictor of group membership was the importance attributed to reducing cancer worry. Women who rated this factor as more important were more likely to be in the surgical group. No women identified the increased risk of heart disease and osteoporosis as issues for consideration. CONCLUSIONS: The desire to reduce cancer worry is likely to be the most important factor in a woman's decision to proceed to prophylactic oophorectomy. In view of the current imprecision in risk estimates given to women considering this option, cancer worry may override a more rational consideration of the costs and benefits of surgery.
机译：背景：关于卵巢癌风险增加的女性在决定进行预防性卵巢切除术，在卵巢癌发生之前进行手术以切除卵巢的决定时认为重要的因素，人们所知甚少。方法：将接受预防性卵巢切除术的妇女（手术组; n = 30）与仍接受卵巢筛查计划的妇女（非手术组; n = 28）进行比较，以评估她们在许多相关决策因素上的重要性。结果：所有受试者中最重要的决策因素是降低卵巢癌的风险，但组成员资格的唯一最佳预测因素是减轻癌症忧虑的重要性。认为此因素更为重要的女性更可能出现在外科手术组中。没有妇女认为心脏病和骨质疏松症的风险增加是需要考虑的问题。结论：减少癌症担忧的愿望可能是女性决定进行预防性卵巢切除术的最重要因素。鉴于目前考虑采用这种方法的女性在风险估计上的不精确性，对癌症的担忧可能会超出对手术成本和收益的更理性考虑。

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