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首页> 外文期刊>Proceedings of the Institution of Mechanical Engineers, Part H. Journal of Engineering in Medicine >Replicating interbody device subsidence with lumbar vertebrae surrogates
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Replicating interbody device subsidence with lumbar vertebrae surrogates

机译：用腰椎替代品复制椎间融合器沉陷

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摘要

Bone surrogates are proposed alternatives to human cadaveric vertebrae for assessing interbody device subsidence. A synthetic vertebra with representations of cortices, endplates and cancellous bone was recently developed as an alternative surrogate to polyurethane foam blocks. The ability of the two surrogates to replicate subsidence has not been fully assessed, and was evaluated by indenting them with ring-shaped indenters and comparing their performance with human cadaveric vertebrae using qualitative characteristics and indentation metrics. The sensitivity of each surrogate to a centrally or peripherally placed indenter was of particular interest. Many indentation characteristics of the foam blocks were similar to those of human cadaveric vertebrae, except their insensitivity to centrally and peripherally placed indenters, owing to their homogeneous mechanical properties. This is distinctly different from the cadaveric vertebrae, where a peripherally placed indenter indented significantly less than a centrally placed indenter, because of endplates. By contrast, the synthetic vertebra was sensitive to peripherally placed indenters owing to its bi-material composition, including a thickened peripheral endplate. However, an overly strong synthetic endplate resulted in unrepresentative indentation shape and depth. Both surrogates produced similar results to human cadaveric vertebrae in certain respects, but neither is accurate enough in terms of material property distribution to model subsidence completely in human cadaveric vertebrae.
机译：骨替代物被提议替代人尸体椎骨以评估椎间融合器的沉降。最近开发出了具有皮质，终板和松质骨表现形式的合成椎骨，作为聚氨酯泡沫块的替代替代品。尚未完全评估这两种替代物复制沉陷的能力，并且通过使用环形压头将它们压痕并使用定性特征和压痕度量将其与人类尸体椎骨的性能进行比较来对其进行评估。每个替代品对位于中心或外围的压头的敏感性特别令人关注。泡沫块的许多压痕特征与人体尸体的压痕特征相似，不同之处在于，由于其均一的机械性能，它们对中央和外围压头不敏感。这与尸体的椎骨截然不同，尸体的椎骨由于端板的缘故，其凹入的凹痕明显小于中央放置的凹痕。相比之下，由于其双重材料组成（包括加厚的外围端板），合成椎骨对放置在外围的压头敏感。但是，过强的合成端板会导致缩进形状和深度无法代表。两种替代物在某些方面都产生了与人体尸体椎骨相似的结果，但在物质属性分布方面都不够准确，无法完全模拟人体尸体椎体的沉降。

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