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首页> 外文期刊>Proceedings of the Institution of Mechanical Engineers, Part H. Journal of Engineering in Medicine >Optical coherence tomography: A potential tool to predict premature rupture of fetal membranes
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Optical coherence tomography: A potential tool to predict premature rupture of fetal membranes

机译：光学相干断层扫描：预测胎膜早破的潜在工具

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摘要

A fundamental question addressed in this study was the feasibility of preterm birth prediction based on a noncontact investigation of fetal membranes in situ. Although the phenomena of preterm birth and the premature rupture of the fetal membrane are well known, currently, there are no diagnostic tools for their prediction. The aim of this study was to assess whether optical coherence tomography could be used for clinical investigations of high-risk pregnancies. The thickness of fetal membranes was measured in parallel by optical coherence tomography and histological techniques for the following types of birth: normal births, preterm births without premature ruptures and births at full term with premature rupture of membrane. Our study revealed that the membrane thickness correlates with the birth type. Normal births membranes were statistically significantly thicker than those belonging to the other two groups. Thus, in spite of almost equal duration of gestation of the normal births and the births at full term with premature rupture, the corresponding membrane thicknesses differed. This difference is possibly related to previously reported water accumulation in the membranes. The optical coherence tomography results were encouraging, suggesting that this technology could be used in future to predict and distinguish between different kinds of births.
机译：在这项研究中解决的一个基本问题是基于对胎儿胎膜的非接触式调查来进行早产预测的可行性。尽管早产现象和胎膜早破现象是众所周知的，但目前，尚无用于预测其的诊断工具。这项研究的目的是评估光学相干断层扫描是否可以用于高危妊娠的临床研究。胎儿膜的厚度通过光学相干断层扫描和组织学技术平行测量，用于以下类型的出生：正常出生，无早产的早产和足月胎膜早破的出生。我们的研究表明，胎膜厚度与出生类型有关。正常分娩的胎膜在统计学上比其他两组的胎膜明显厚。因此，尽管正常分娩的妊娠时间和足月分娩的早产几乎相等，但相应的胎膜厚度却有所不同。这种差异可能与先前报道的膜中水的积累有关。光学相干断层扫描技术的结果令人鼓舞，这表明该技术将来可用于预测和区分不同种类的出生。

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