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首页> 外文期刊>Proceedings of the Institution of Mechanical Engineers, Part H. Journal of Engineering in Medicine >Swelling and mechanical properties of physically crosslinked poly(vinyl alcohol) hydrogels
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Swelling and mechanical properties of physically crosslinked poly(vinyl alcohol) hydrogels

机译：物理交联的聚乙烯醇水凝胶的溶胀和力学性能

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摘要

Physically crosslinked poly(vinyl alcohol) gels are versatile biomaterials due to their excellent biocompatibility. In the past decades, physically crosslinked poly(vinyl alcohol) and poly(vinyl alcohol)-based hydrogels have been extensively studied for biomedical applications. However, these materials have not yet been implemented due to their mechanical strength. Physically crosslinked poly(vinyl alcohol) gels consist of a swollen amorphous network of poly(vinyl alcohol) physically crosslinked by microcrystallites. Although the mechanical properties can be improved to some extent by controlling the distribution of microcrystallites on the nano- and micro-scales, enhancing the mechanical properties while maintaining high water content remains very difficult. It may be technologically impossible to significantly improve the mechanical properties while keeping the gel's high water absorbance ability using conventional fabrication methods. Physical and chemical understandings of the swelling and mechanical properties of physically crosslinked poly(vinyl alcohol) gels are considered here; some promising strategies for their practical applications are presented. This review focuses more on the recent studies on swelling and mechanical properties of poly(vinyl alcohol) hydrogels, prepared using only poly(vinyl alcohol) and pure water with no other chemicals, as potential biomedical materials.
机译：物理交联的聚乙烯醇凝胶由于其出色的生物相容性而成为通用的生物材料。在过去的几十年中，物理交联的聚乙烯醇和基于聚乙烯醇的水凝胶已被广泛研究用于生物医学应用。但是，由于它们的机械强度，这些材料尚未实现。物理交联的聚乙烯醇凝胶由微晶物理交联的聚乙烯醇溶胀的无定形网络组成。尽管可以通过控制纳米和微米级微晶的分布在一定程度上改善机械性能，但是在保持高水含量的同时提高机械性能仍然非常困难。使用传统的制造方法，在保持凝胶的高吸水能力的同时，从技术上讲不可能显着改善机械性能。这里考虑了对物理交联的聚乙烯醇凝胶的溶胀和机械性能的物理和化学理解;提出了一些有实际应用前景的策略。这篇综述更多地关注于聚乙烯醇水凝胶的溶胀和机械性能的最新研究，该研究仅使用聚乙烯醇和纯水而没有其他化学物质作为潜在的生物医学材料制备。

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