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The mycotoxic risk: danger and health impact in animal production

机译:霉菌毒素风险:对动物生产的危害和健康影响

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Animal exposure to mycotoxin contaminated feeds demonstrates the effect of these natural contaminants on animal performances and on safety of food products of animal origin. Aflatoxine B-1, fumonisin B-1 and deoxynivalenol have been found to alter immune response in pigs with putative consequences in terms of susceptibility to infections. The same toxins modulate liver biotransformation enzymes, leading to possible changes in the normal fate or action of xenobiotic or endogenous compounds. In poultry, high exposure to fumonisins leads to lower duck or turkey production. Tissue residues of fumonisins have been detected in hepatic or renal tissues of these animals when exposed to levels corresponding to the upper limit of the European tolerance for maize. In ruminants, gliotoxin, patulin, roquefortin C and mycophenolic acid have been investigated as possible contaminants of fodder. All these toxins disturb ruminal fermentations. Through a national survey, residues of aflatoxin M-1 and ochratoxin A have been detected in commercial milks. However, the measured concentrations are below the European regulatory level for each toxin.
机译:动物暴露于受霉菌毒素污染的饲料中,证明了这些天然污染物对动物生产性能和动物源食品安全性的影响。已发现黄曲霉毒素B-1,伏马菌素B-1和脱氧雪茄烯醇会改变猪的免疫反应,对感染的敏感性可能会带来后果。相同的毒素调节肝脏的生物转化酶,导致异种或内源性化合物的正常命运或作用可能发生变化。在家禽中,高度暴露于伏马菌素会降低鸭肉或火鸡的产量。当暴露于与欧洲玉米耐性上限相对应的水平时,在这些动物的肝或肾组织中检测到伏马菌素的组织残留。在反刍动物中,已经研究了gliotoxin,patulin,roquefortin C和霉酚酸作为饲料的可能污染物。所有这些毒素干扰瘤胃发酵。通过一项全国调查,在商业牛奶中发现了黄曲霉毒素M-1和曲霉毒素A的残留。但是,每种毒素的测量浓度均低于欧洲法规水平。

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