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Overview of antiarrhythmic drug therapy for supraventricular tachycardia in children

机译:小儿室上性心动过速抗心律失常药物治疗概述

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摘要

Antiarrhythmic drug therapy remains the mainstay of therapy for pediatric supraventricular tachycardia (SVT). In order to appropriately treat pediatric arrhythmias pharmacologically, an understanding of the mechanisms of action, efficacy, adverse effects, and interactions for the different antiarrhythmics is required. This article provides an overview of the pharmacologic treatment options for children with SVT. We review the classification systems, mechanisms of action, pharmacokinetics, and pharmacodynamics of the available antiarrhythmics used in pediatric SVT. We also outline the side effects, drug interactions, and evidence available for the efficacy of these different medications in the pediatric age group.
机译:抗心律失常药物疗法仍然是小儿室上性心动过速(SVT)的主要疗法。为了从药理学上适当地治疗小儿心律失常,需要了解不同抗心律不齐药物的作用机制,疗效,不良反应和相互作用。本文概述了SVT儿童的药物治疗选择。我们回顾了儿科SVT中可用抗心律不齐药物的分类系统,作用机制,药代动力学和药效学。我们还概述了这些不良药物的副作用,药物相互作用以及可用于儿童年龄组的证据。

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