ESI-MS Studies of Silver Ion Competitive Interaction with Cysteine-Containing Peptides and Sulfur-Containing Amino Acids

Novikov AV; Bublyaev RA; Krasnov NV; Kozmin YP; Mirgorodskaya OA

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ESI-MS Studies of Silver Ion Competitive Interaction with Cysteine-Containing Peptides and Sulfur-Containing Amino Acids

机译：ESI-MS研究银离子与半胱氨酸肽和含硫氨基酸的竞争性相互作用

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The paper deals with investigation of silver ion interaction with sulfur-bearing amino acids and cysteine-bearing peptides using an electrospray ionisation orthogonal ion introduction time-of-flight (ESI-o-TOF) mass spectrometer. It has been shown that Cys and Hcy demonstrate the largest affinity for silver, both in relation to methionine and cysteine residues in peptides. The studies have for the first time revealed the effect of predominant forming of ions containing two silver atoms per a sulfhydryl group of cysteine-bearing peptides if the nearest microenvironment does not hinder this.

机译：本文使用电喷雾电离正交离子引入飞行时间（ESI-o-TOF）质谱仪研究银离子与含硫氨基酸和含半胱氨酸的肽的相互作用。已经显示，相对于肽中的蛋氨酸和半胱氨酸残基，Cys和Hcy显示出对银的最大亲和力。研究首次揭示了如果最接近的微环境不妨碍这种现象，则主要形成每个半胱氨酸携带肽的巯基含两个银原子的离子的作用。

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《Protein and peptide letters》 |2010年第11期|共6页
作者
Novikov AV; Bublyaev RA; Krasnov NV; Kozmin YP; Mirgorodskaya OA;
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原文格式 PDF
正文语种 eng
中图分类蛋白质;
关键词
Sulfur-bearing amino acids; cysteine-bearing peptides; silver; affinity; ESI-O-TOF;

机译：含硫氨基酸;半胱氨酸肽;银;亲和力;ESI-O-TOF;

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1. ESI-MS Studies of Silver Ion Competitive Interaction with Cysteine-Containing Peptides and Sulfur-Containing Amino Acids [J] . Novikov AV, Bublyaev RA, Krasnov NV, Protein and peptide letters . 2010,第11期

机译：ESI-MS研究银离子与半胱氨酸肽和含硫氨基酸的竞争性相互作用
2. CZE of sulfur-containing amino acids and peptides and its application to the quantitative study of heavy metal-caused thiol oxidations [J] . Schmidt A.-C., Lauckner S., Lindner K. Chromatographia . 2012,第11a12期

机译：含硫氨基酸和肽的CZE及其在重金属引起的巯基氧化反应定量研究中的应用
3. CZE of Sulfur-Containing Amino Acids and Peptides and Its Application to the Quantitative Study of Heavy Metal-Caused Thiol Oxidations [J] . Anne-Christine Schmidt, Stefanie Lauckner, Katja Lindner Chromatographia . 2012,第11a12期

机译：含硫氨基酸和肽的CZE及其在重金属引起的巯基氧化反应定量研究中的应用
4. ESI-MS Gas-Phase Carbene Philicity Study of Common Amino Acids in Peptides via Labeling Electrospray Deposition (LESD) [C] . Douglas Steiner, Daniel Therrien, Katherine Steiner, American Society for Mass Spectrometry Conference on Mass Spectrometry and Allied Topics . 2012

机译：ESI-MS气相Carbene通过标记电喷雾沉积（LESD）肽中常见氨基酸的异丙蛋白基础研究
5. Molecular modeling studies of the interaction of peptides containing aromatic amino acids with (dA-dT)(10). [D] . De Jesus Ruiz, Marco Antonio. 1996

机译：含芳香族氨基酸的肽与（dA-dT）（10）相互作用的分子模型研究。
6. Studies on the determination of the sequence of amino acids in peptides and proteins. 3. The synthesis of 3-(4′-dimethylamino-3′:5′-dinitrophenyl)hydantoin derivatives of various amino acids and their use for the determination of N-terminal amino acids [O] . G. G. Evans, W. S. Reith 1954

机译：确定肽和蛋白质中氨基酸序列的研究。 3.各种氨基酸的3-（4-二甲基氨基-3：5-二硝基苯基）乙内酰脲衍生物的合成及其在测定N端氨基酸中的用途
7. Growth Prediction of Chicks from Dietary Amino Acid Profiles with Special Reference to Interactions between Sulfur-Containing and Aromatic Amino Acids. [O] . Supaporn ISARIYODOM, Hiroshi OHSHIMA, Masahiro GOTO, 1991

机译：特别参考含硫和芳族氨基酸之间的相互作用的膳食氨基酸谱的雏鸡生长预测。
8. Studies Related to Primitive Chemistry. A Preliminary Investigation of the Applicability of Proton and Nitrogen-14 Nuclear Magnetic Resonance to the Characterization of Interactions Between Amino Acid and Nucleic Acid Constituents and a Discussion of Previous Work on These Interactions and Their Possible Relation to Prebiotic Synthesis of Biopolymers [R] . Manatt, S. L., Cohen, E. A., Shiller, A. M., 1973

机译：与原始化学相关的研究。质子和氮-14核磁共振对氨基酸和核酸组分相互作用表征的适用性的初步研究，以及对这些相互作用的前期工作的讨论及其与生物聚合物益生元合成的可能关系

ESI-MS Studies of Silver Ion Competitive Interaction with Cysteine-Containing Peptides and Sulfur-Containing Amino Acids

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