Assessment between phosphoglycerate dehydrogenase gene and schizophrenia in Korean population.

Kim HJ; Ban JY; Park HJ; Kim SK; Kang SW; Chung JH; Park JK; Kim JW

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Assessment between phosphoglycerate dehydrogenase gene and schizophrenia in Korean population.

机译：朝鲜族人群磷酸甘油酸脱氢酶基因与精神分裂症之间的评估。

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Converging evidences including genetic study have supported the hypofunction hypothesis of glutamatergic neurotransmission through the N-methyl-D-aspartate-type glutamate receptor in schizophrenic brains (Kazuo et al., 2005). D-serine is an endogenous ligand for the glycine site of N-methyl-D-aspartate receptor. D-serine is formed L-serine by serine racemase, and 3-phosphogly-cerate dehydrogenase (3-PHGDH) is the first and rate-limiting enzyme of L-serine biosynthesis. PHGDH gene is located on chromosome Ipl2, and its functions are various: PHGDH activity, electron carrier activity, brain development, and cofactor binding (De Koning, 2006)

机译：包括遗传学研究在内的越来越多的证据支持了精神分裂症脑中通过N-甲基-D-天冬氨酸型谷氨酸受体进行谷氨酸能神经传递功能低下的假说（Kazuo等，2005）。 D-丝氨酸是N-甲基-D-天冬氨酸受体的甘氨酸位点的内源性配体。 D-丝氨酸是由丝氨酸消旋酶形成的L-丝氨酸，而3-磷酸-铈酸脱氢酶（3-PHGDH）是L-丝氨酸生物合成的第一种酶和限速酶。 PHGDH基因位于Ipl2染色体上，其功能多种多样：PHGDH活性，电子载体活性，大脑发育和辅因子结合（De Koning，2006）

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《Psychiatric genetics》 |2009年第3期|共1页
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Kim HJ; Ban JY; Park HJ; Kim SK; Kang SW; Chung JH; Park JK; Kim JW;
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中图分类精神病学;
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1. Assessment between phosphoglycerate dehydrogenase gene and schizophrenia in Korean population. [J] . Kim HJ, Ban JY, Park HJ, Psychiatric genetics . 2009,第3期

机译：朝鲜族人群磷酸甘油酸脱氢酶基因与精神分裂症之间的评估。
2. Association of histone deacetylase genes with schizophrenia in Korean population. [J] . Kim T, Park JK, Kim HJ, Psychiatry research . 2010,第2期

机译：组蛋白脱乙酰基酶基因与韩国人精神分裂症的关联。
3. A family-based association study of T1945C polymorphism in the proline dehydrogenase gene and schizophrenia in the Chinese population. [J] . Fan JB, Ma J, Zhang CS, Neuroscience Letters: An International Multidisciplinary Journal Devoted to the Rapid Publication of Basic Research in the Brain Sciences . 2003,第3期

机译：基于家族的脯氨酸脱氢酶基因T1945C多态性与中国人群精神分裂症的关联研究。
4. Environmental Impact Assessment (EIA) of Wind Power Generation Plan in Korea [C] . Hyosung Sun International Conference on Wind Turbine Noise . 2018

机译：韩国风力发电计划的环境影响评估（EIA）
5. The effects of the proline dehydrogenase and the reticulon-4 receptor genes in the development of schizophrenia. [D] . Lazar, Noah Lawrence. 2010

机译：脯氨酸脱氢酶和reticulon-4受体基因在精神分裂症发展中的作用。
6. Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3 enhancer. [O] . J D Firth, B L Ebert, C W Pugh, 1994

机译：磷酸甘油酸激酶1和乳酸脱氢酶A基因中的氧调节控制元件：与促红细胞生成素3增强子的相似性。
7. Oxygen-regulated control elements in the phosphoglycerate kinase 1 and lactate dehydrogenase A genes: similarities with the erythropoietin 3' enhancer. [O] . Firth, JD, Ebert, BL, Pugh, CW, 1994

机译：磷酸甘油酸激酶1和乳酸脱氢酶A基因中的氧调节控制元件：与促红细胞生成素3'增强子的相似性。

Assessment between phosphoglycerate dehydrogenase gene and schizophrenia in Korean population.

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