Transcatheter Aortic Valve Replacement: A Transformative Therapy

SorajjaP.

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Transcatheter Aortic Valve Replacement: A Transformative Therapy

机译：经导管主动脉瓣置换术：一种转化疗法

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The health care profession is a highly privileged one, in which professionals are able to both witness and actively participate in the delivery of care that transforms patients' lives, as well as the profession itself.In this light, we have been beholden to the rapid evolution of transcatheter aortic valve replacement (TAVR), a therapy whose influence has stretched far beyond simply being a mechanical solution for treating aortic stenosis (AS). To date, there have been over 100,000 patients who have undergone TAVR worldwide, including over -8000 individuals in the United States (US) since commercial approval in 2011.1 Moreover, the number of treated patients is expected to grow exponentially due to population aging. In one study, it was estimated that -9000 individuals in the US and -19,000 persons in Europe become eligible for TAVR each year.2 Through multiple clinical investigations, it is now widely accepted that TAVR is an efficacious therapy for patients with severe symptomatic AS who are either inoperable or at high-surgical risk for open surgical aortic valve replacement (SAVR).

机译：卫生保健行业是一种特权很高的行业，在该行业中，专业人员能够见证并积极参与提供改变患者生活的护理，以及该行业本身。经导管主动脉瓣置换术（TAVR）的发展，其影响已经远远超出了单纯的机械方法来治疗主动脉瓣狭窄（AS）的范围。迄今为止，自2011年获得商业批准以来，全世界已有100,000多名患者接受了TAVR，其中包括-8000多名美国患者。1此外，由于人口老龄化，预计接受治疗的患者人数将呈指数增长。在一项研究中，估计美国每年-9000人和欧洲-19,000人有资格获得TAVR。2通过多项临床研究，现已广泛接受TAVR是对重度症状性AS患者有效的治疗方法不能进行手术主动脉瓣置换术（SAVR）或手术风险较高的患者。

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《Progress in Cardiovascular Diseases》 |2014年第6期|共2页
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SorajjaP.;
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中图分类心脏、血管（循环系）疾病;
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4. Classification of Aortic Stenosis Before and After Transcatheter Aortic Valve Replacement Using Cardio-mechanical Modalities* [C] . Chenxi Yang, Banish Ojha, Nicole D. Aranoff, . 2020

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Transcatheter Aortic Valve Replacement: A Transformative Therapy

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