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首页> 外文期刊>Progress in brain research >Spinal cord neural organization controlling the urinary bladder and striated sphincter.
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Spinal cord neural organization controlling the urinary bladder and striated sphincter.

机译：脊髓神经组织控制膀胱和横纹括约肌。

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摘要

The storage and elimination of urine requires the coordination of activity between the autonomic nervous system (thoracolumbar sympathetic and sacral parasympathetic divisions) controlling the urinary bladder and urethra and the lumbosacral somatic motoneurons innervating the striated sphincter and pelvic floor muscles. These three efferent systems involved in the control of lower urinary tract function receive segmental sensory information from various visceral organs and the perineum, as well as inputs from supraspinal regions. Ascending and descending connections between the various spinal segments levels and supraspinal regions provide the reflex substrates participating in normal bladder continence and micturition reflexes. Many of the actions of descending and segmental reflexes are mediated by excitatory and inhibitory sacral spinal interneurons located within the region of the parasympathetic preganglionic autonomic neurons and the sphincter ventral horn motoneurons. This review will: (1) discuss the basic organization and spinal elements of the reflex pathways subserving continence and micturition; (2) describe features of the identified sacral interneuronal circuitry contributing to the control of the bladder and sphincter function; and (3) discuss how changes in the control of these reflex pathways and neurons may contribute to abnormal patterns of bladder and sphincter function commonly observed following spinal cord injury.
机译：尿液的储存和消除需要协调控制膀胱和尿道的自主神经系统（胸腰交感和副交感分裂）与支配横纹括约肌和骨盆底肌肉的腰s体运动神经元之间的活动协调。这三个控制下尿路功能的传出系统接收来自各种内脏器官和会阴的节段性感觉信息，以及来自脊髓上区域的输入。各个脊柱节段水平和脊柱上区域之间的上升和下降连接提供了参与正常膀胱节制和排尿反射的反射基质。降反射和节段性反射的许多作用是由位于副交感神经节前自主神经元和括约肌腹角运动神经元区域内的兴奋性和抑制性s神经元介导的。这篇综述将：（1）讨论维持节制和排尿的反射途径的基本组织和脊柱元素; （2）描述所确定的to神经内电路的特征，这些特征有助于控制膀胱和括约肌功能; （3）讨论了对这些反射途径和神经元的控制方式的改变如何可能导致脊髓损伤后通常观察到的膀胱和括约肌功能异常模式。

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