...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Progress in brain research >Activation and coordination of spinal motoneuron pools after spinal cord injury.
【24h】

Activation and coordination of spinal motoneuron pools after spinal cord injury.

机译：脊髓损伤后脊髓运动神经元池的激活和协调。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Goal-directed movements of the limbs involve the coordinated activation of dozens of muscles. The neural signals activating these muscles are organized at spinal and supraspinal levels, the end result being trains of action potentials delivered to muscles by ensembles of spinal motoneurons (MNs). A new modelling approach has allowed us to visualize the activity of MNs controlling cat hindlimb locomotion. This reveals a rostrocaudal oscillation of MN activity distributed over about 30 mm of the lumbosacral spinal cord. The coordination and topographical distribution of MN pools thus revealed put an interesting perspective on the restoration of motor function with regeneration and neuroprosthetic techniques. Recent progress in the area of intraspinal microstimulation (ISMS) is reviewed, including the synthesis of locomotor movements with a small number of implanted microwires, eliciting movements after a spinal transection and facilitating weak voluntary movements with subliminal ISMS. We suggest that neuroprostheses may be useful in maximizing the benefits of neural regeneration in the future.
机译：四肢的目标定向运动涉及数十种肌肉的协调激活。激活这些肌肉的神经信号被组织在脊柱和脊柱上水平，最终结果是通过脊髓运动神经元（MNs）的集合传递给肌肉的一系列动作电位。一种新的建模方法使我们能够可视化控制猫后肢运动的MN的活动。这揭示了MN活动的后尾骨振荡分布在腰ac脊髓的约30mm上。从而揭示了MN池的协调性和地形分布，为通过再生和神经修复技术恢复运动功能提出了有趣的观点。综述了椎管内微刺激（ISMS）领域的最新进展，包括使用少量植入的微丝合成运动运动，在脊椎横断后引起运动以及通过下意识ISMS促进较弱的自发运动。我们建议神经假体在将来最大化神经再生的益处中可能有用。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号