Increasing plasticity and functional recovery of the lesioned spinal cord.

Schwab ME

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Increasing plasticity and functional recovery of the lesioned spinal cord.

机译：病变脊髓的可塑性提高和功能恢复。

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In vitro assays have shown that adult CNS tissue, in particular oligodendrocytes and myelin, contains several molecular constituents (Nogo-A/NI-220, MAG, several proteoglycans) which exert neurite growth inhibitory activity. Elimination of oligodendrocytes or myelin, or application of antibodies against some of these constituents enhance regenerative growth and compensatory sprouting of lesioned and unlesioned fiber tracts in spinal cord and brain. Enhanced growth is paralleled by various degrees of functional recovery.

机译：体外试验表明，成年的中枢神经系统组织，特别是少突胶质细胞和髓鞘，含有几种具有神经突生长抑制活性的分子成分（Nogo-A / NI-220，MAG，几种蛋白聚糖）。消除少突胶质细胞或髓磷脂，或应用针对其中一些成分的抗体，可增强脊髓和大脑中病变和未病变的纤维束的再生生长和代偿性发芽。增长的增长与各种程度的功能恢复并行。

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《Progress in brain research》 |2002年第0期|共9页
作者
Schwab ME;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Neurites; Neuronal Plasticity; Spinal Cord Injuries; 神经突; 神经元可塑性; 脊髓损伤;

机译：Neurites;Neuronal Plasticity;Spinal Cord Injuries;神经突;神经元可塑性;脊髓损伤;

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1. Increasing plasticity and functional recovery of the lesioned spinal cord. [J] . Schwab ME Progress in brain research . 2002,第0期

机译：病变脊髓的可塑性提高和功能恢复。
2. Ex vivo adenoviral vector-mediated neurotrophin gene transfer to olfactory ensheathing glia: effects on rubrospinal tract regeneration, lesion size, and functional recovery after implantation in the injured rat spinal cord. [J] . Ruitenberg MJ, Plant GW, Hamers FP, The Journal of Neuroscience: The Official Journal of the Society for Neuroscience . 2003,第18期

机译：体外腺病毒载体介导的神经营养蛋白基因转移到嗅鞘神经胶质细胞：损伤鼠脊髓植入后对脊髓脊髓束再生，病变大小和功能恢复的影响。
3. Ensheathing cells and methylprednisolone promote axonal regeneration and functional recovery in the lesioned adult rat spinal cord. [J] . Nash HH, Borke RC, Anders JJ The Journal of Neuroscience: The Official Journal of the Society for Neuroscience . 2002,第16期

机译：鞘细胞和甲基泼尼松龙可促进成年大鼠脊髓轴突再生和功能恢复。
4. Quantitative analysis of neural plasticity in motorcortex during functional recovery post spinal cord injury [C] . Huo Yan, Li Ping, Ma Chaolin, 32nd Annual International Conference of the IEEE Engineering in Medicine and Biology Society . 2010

机译：脊髓损伤后功能恢复期间运动皮质神经可塑性的定量分析
5. The effect of electrolytic lesion and neural implants on glial fibrillary acidic protein expression in the rat spinal cord. [D] . Falconer, Robert J. 1989

机译：电解损伤和神经植入物对大鼠脊髓胶质纤维酸性蛋白表达的影响。
6. Comparison of Functional Recovery of Manual Dexterity after Unilateral Spinal Cord Lesion or Motor Cortex Lesion in Adult Macaque Monkeys [O] . Florence Hoogewoud, Adjia Hamadjida, Alexander F. Wyss, 2013

机译：成年猕猴单侧脊髓损伤或运动皮质损伤后手部敏捷功能恢复的比较
7. Olfactory ensheathing cells, olfactory nerve fibroblasts and biomatrices to promote long-distance axon regrowth and functional recovery in the dorsally hemisected adult rat spinal cord. [O] . Deumens, Ronald, Koopmans, G C, Honig, W M M, 2006

机译：嗅鞘细胞，嗅神经成纤维细胞和生物基质促进背侧成年大鼠脊髓的长轴突再生和功能恢复。

Increasing plasticity and functional recovery of the lesioned spinal cord.

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