...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Progress in brain research >The mental self.
【24h】

The mental self.

机译：精神上的自我。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In meditation both the quality and the contents of consciousness may be voluntarily changed, making it an obvious target in the quest for the neural correlate of consciousness. Here we present the results of a positron emission tomography study of yoga nidra relaxation meditation when compared with the normal resting conscious state. Meditation is accompanied by a relatively increased perfusion in the sensory imagery system: hippocampus and sensory and higher order association regions, with decreased perfusion in the executive system: dorsolateral prefrontal cortex, anterior cingulate gyrus, striatum, thalamus, pons, and cerebellum. To identify regions active in both systems we performed a principal component analysis of the results. This separated the blood flow data into two groups of regions, explaining 25 and 18% of their variance: One group corresponded to the executive system, and the other to the systems supporting sensory imagery. A small group of regions contributed considerably to both networks: medial parietal and medial prefrontal cortices, together with the striatum. The inclusion of the striatum and our subsequent finding of increased striatal dopamine binding to D2 receptors during meditation suggested dopaminergic regulation of this circuit. We then investigated the neural networks supporting episodic retrieval of judgments of individuals with different degrees of self-relevance, in the decreasing order: self, best friend, and the Danish queen. We found that all conditions activated a medial prefrontal - precuneus/posterior cingulate cortex, thalamus, and cerebellum. This activation occurred together with the activation of the left lateral prefrontal/temporal cortex. The latter was dependent on the requirement of retrieval of semantic information, being most pronounced in the "queen" condition. Transcranial magnetic stimulation, targeting precuneus, was then applied to the medial parietal region to transiently disrupt the normal function of the circuitry. We found a decreased efficiency of retrieval of self-judgment compared to the judgment of best friend. This shows that the integrity of the function of precuneus is essential for self-reference, but not for reference to others.
机译：在冥想中，意识的质量和内容均可自愿改变，使其成为寻求意识的神经相关性的明显目标。在这里，我们介绍了与正常的休息意识状态相比，瑜伽nidra放松冥想的正电子发射断层扫描研究的结果。冥想伴随着感觉影像系统的相对灌注增加：海马体和感觉和较高阶的联想区域，而执行系统的灌注减少：背外侧前额叶皮层，前扣带回，纹状体，丘脑，脑桥和小脑。为了确定两个系统中活跃的区域，我们对结果进行了主成分分析。这将血流数据分为两组区域，解释了它们的方差的25％和18％：一组对应于执行系统，另一组对应于支持感觉图像的系统。一小部分地区对这两个网络都做出了很大贡献：内侧顶叶和内侧前额叶皮层以及纹状体。纹状体的包含以及我们随后在冥想过程中发现纹状体多巴胺与D2受体结合增加的发现，提示该电路的多巴胺能调节。然后，我们研究了支持对具有不同自我相关程度的个体进行断言检索的神经网络，这些个体以降序排列：自我，最好的朋友和丹麦皇后。我们发现所有情况都激活了内侧前额叶-丘脑前/后扣带回皮层，丘脑和小脑。该激活与左侧外侧前额叶/颞皮质的激活一起发生。后者取决于检索语义信息的要求，在“ queen”条件下最为明显。然后，以颅前神经为靶点的经颅磁刺激被施加到顶壁内侧区域，以瞬时破坏电路的正常功能。与最好的朋友的判断相比，我们发现自我判断的检索效率降低了。这表明，足神经功能的完整性对于自我参照是至关重要的，但对于参照他人而言则是必不可少的。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号