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Which pathways must be spared in the injured human spinal cord to retain cardiovascular control?

机译:在受伤的人类脊髓中必须保留哪些途径才能保持心血管控制?

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摘要

Cardiovascular abnormalities following spinal cord injury are attributed to autonomic instability caused by a combination of changes occurring within the spinal cord, including loss of descending autonomic control and plastic changes within spinal and peripheral circuits. Previous animal studies have shown that localized disruption of the descending vasomotor pathways results in cardiovascular changes similar to those observed following cord injury. However, the location of these pathways in humans is uncertain. This chapter presents clinical and histopathological findings from individuals with spinal cord injury that associates a common area of white matter destruction with severe cardiovascular symptoms. These data provide evidence that descending vasomotor pathways in the human spinal cord project through the dorsal aspects of the lateral funiculus.
机译:脊髓损伤后的心血管异常归因于脊髓内发生的各种变化所引起的自主神经不稳定,这些变化包括丧失自主神经控制能力下降以及脊髓和周围回路内的塑性变化。先前的动物研究表明,下行血管舒缩通路的局部破坏会导致心血管变化,类似于在脊髓损伤后观察到的变化。但是,这些途径在人类中的位置尚不确定。本章介绍了脊髓损伤个体的临床和组织病理学发现,这些发现将常见的白质破坏与严重的心血管症状联系在一起。这些数据提供了证据,表明人类脊髓中的血管舒缩途径通过侧耳的背侧突出。

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