Simulation of GABA function in the basal ganglia: computational models of GABAergic mechanisms in basal ganglia function.

Wickens JR; Arbuthnott GW; Shindou T

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Simulation of GABA function in the basal ganglia: computational models of GABAergic mechanisms in basal ganglia function.

机译：基底神经节中GABA功能的模拟：基底神经节功能中GABA能机制的计算模型。

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This chapter outlines current interpretation of computational aspects of GABAergic circuits of the striatum. Recent hypotheses and controversial matters are reviewed. Quantitative aspects of striatal synaptology relevant to computational models are considered, with estimates of the connectivity of the spiny projection neurons and fast-spiking interneurons. Against this background, insights into the computational properties of inhibitory circuits based on analysis and simulation of simple models are discussed. The paper concludes with suggestions for further theoretical and experimental studies.

机译：本章概述了纹状体GABA能电路的计算方面的最新解释。最近的假设和有争议的问题进行了审查。考虑到与计算模型有关的纹状体突触学的定量方面，并评估了多刺投射神经元和快速掺和的中间神经元的连通性。在此背景下，讨论了基于简单模型的分析和仿真对抑制电路的计算特性的见解。本文最后提出了进一步理论和实验研究的建议。

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《Progress in brain research》 |2007年第0期|共17页
作者
Wickens JR; Arbuthnott GW; Shindou T;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Action Potentials; Animals; Basal Ganglia; Computer Simulation; Humans; Neural Inhibition; 动作电位; 动物; 基底神经节; 计算机模拟; 神经抑制; 神经网络(计算机); 神经通路;

机译：Action Potentials;Animals;Basal Ganglia;Computer Simulation;Humans;Neural Inhibition;动作电位;动物;基底神经节;计算机模拟;神经抑制;神经网络(计算机);神经通路;

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1. Simulation of GABA function in the basal ganglia: computational models of GABAergic mechanisms in basal ganglia function. [J] . Wickens JR, Arbuthnott GW, Shindou T Progress in brain research . 2007,第0期

机译：基底神经节中GABA功能的模拟：基底神经节功能中GABA能机制的计算模型。
2. Modeling effect of GABAergic current in a basal ganglia computational model [J] . Felix Njap, Jens Christian Claussen, Andreas Moser, Cognitive Neurodynamics . 2012,第4期

机译：基底神经节计算模型中GABA能电流的建模效果
3. Epigenetic mechanisms expressed in basal ganglia GABAergic neurons differentiate schizophrenia from bipolar disorder. [J] . Veldic M, Kadriu B, Maloku E, Schizophrenia research . 2007,第1a3期

机译：在基底神经节GABA能神经元中表达的表观遗传机制将精神分裂症与双相情感障碍区分开来。
4. fMRI experiments and computational models of the function of the prefrontal cortex and the basal ganglia: a review [C] . Monchi, O. . 2005

机译：前额叶皮质和基底神经节功能的功能磁共振成像实验和计算模型：综述
5. Reward-based learning and basal ganglia: A biologically realistic, computationally explicit theory. [D] . Brucher, Fernando Andres. 2000

机译：基于奖励的学习和基底神经节：一种生物学上可行的，计算明确的理论。
6. Modeling effect of GABAergic current in a basal ganglia computational model [O] . Felix Njap, Jens Christian Claussen, Andreas Moser, 2012

机译：基底神经节计算模型中GABA能电流的建模效果
7. Modeling effect of GABAergic current in a basal ganglia computational model [O] . Njap, Felix, Claussen, Jens Christian, Moser, Andreas, 2013

机译：GaBaergic电流在基底神经节计算中的模拟效应模型

Simulation of GABA function in the basal ganglia: computational models of GABAergic mechanisms in basal ganglia function.

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