• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Progress in brain research >Spine dynamics and synapse remodeling during LTP and memory processes.
【24h】

Spine dynamics and synapse remodeling during LTP and memory processes.

机译：LTP和记忆过程中的脊柱动力学和突触重塑。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

While changes in the efficacy of synaptic transmission are believed to represent the physiological bases of learning mechanisms, other recent studies have started to highlight the possibility that a structural reorganization of synaptic networks could also be involved. Morphological changes of the shape or size of dendritic spines or of the organization of postsynaptic densities have been described in several studies, as well as the growth and formation following stimulation of new protrusions. Confocal in vivo imaging experiments have further revealed that dendritic spines undergo a continuous turnover and replacement process that may vary as a function of development, but can be markedly enhanced by sensory activation or following brain damage. The implications of these new aspects of plasticity for learning and memory mechanisms are discussed.
机译：虽然突触传递功效的变化被认为代表了学习机制的生理基础，但其他近期研究也开始突显突触网络也可能参与结构重组的可能性。树突棘的形状或大小或突触后密度组织的形态学变化，以及在刺激新突起后的生长和形成都已被描述。共聚焦体内成像实验进一步表明，树突棘经历了连续的翻转和替换过程，该过程可能会随着发育而变化，但可以通过感觉激活或脑损伤后得到明显增强。讨论了可塑性这些新方面对学习和记忆机制的影响。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号