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首页> 外文期刊>Public health >Socio-economic status and the risk of liver cancer mortality: a prospective study in Korean men.
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Socio-economic status and the risk of liver cancer mortality: a prospective study in Korean men.

机译：社会经济地位和肝癌死亡风险：韩国男性前瞻性研究。

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OBJECTIVE: To examine the association between socio-economic status (SES) and liver cancer mortality among Korean men. STUDY DESIGN: Prospective cohort study METHODS: Data were acquired from a large, prospective cohort study that included 548,530 civil service workers aged 30-59 years who had undergone health examination in 1998 provided by the Korean National Health Insurance System. Information on lifestyle and demographic characteristics was acquired through self-administered questionnaires. The main outcome event was mortality from liver cancer. Cox proportional hazards model was used to estimate relative risks (RRs) and 95% confidence intervals (95% CIs) after adjusting for age, body mass index, fasting serum glucose, alcohol consumption, smoking and hepatitis B surface antigen (HBsAg) status. RESULTS: Liver cancer mortality differentials relating to SES were statistically significant and consistent in the fully adjusted model. Compared with the highest SES category, excess risk associated with liver cancer mortality was observed with decreasing SES levels: the RRs in the upper middle, lower middle and low SES categories were 1.35 (95% CI 1.13-1.61), 1.54 (95% CI 1.28-1.86) and 1.72 (95% CI 1.45-2.04), respectively. There was no effect modification by HBsAg status on the association between SES and liver cancer mortality. CONCLUSIONS: This study demonstrated an inverse association between SES and liver cancer mortality, suggesting that SES is an independent predictor of liver cancer mortality. The policies and interventions regarding prevention of liver cancer need to focus on disadvantaged groups in order to reduce health disparities related to liver cancer.
机译：目的：探讨韩国男性社会经济地位（SES）与肝癌死亡率之间的关系。研究设计：前瞻性队列研究方法：数据来自一项大型前瞻性队列研究，该研究包括548,530名30-59岁的公务员，他们于1998年接受了韩国国民健康保险系统的健康检查。通过自我管理的问卷调查获得了有关生活方式和人口统计学特征的信息。主要的预后事件是肝癌的死亡率。调整年龄，体重指数，空腹血糖，饮酒，吸烟和乙肝表面抗原（HBsAg）状态后，使用Cox比例风险模型估算相对风险（RRs）和95％置信区间（95％CI）。结果：与SES相关的肝癌死亡率差异在统计学上是显着的，并且在完全调整的模型中是一致的。与最高SES类别相比，随着SES水平的降低，观察到与肝癌死亡率相关的额外风险：中，低，中和低SES类别的RR为1.35（95％CI 1.13-1.61），1.54（95％CI） 1.28-1.86）和1.72（95％CI 1.45-2.04）。 HBsAg状态对SES与肝癌死亡率之间的关联没有影响。结论：这项研究证明SES与肝癌死亡率之间呈负相关，表明SES是肝癌死亡率的独立预测因子。预防肝癌的政策和干预措施应集中于弱势群体，以减少与肝癌有关的健康差异。

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