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Risk factors for overall and persistent diarrhoea in infancy in Antalya, Turkey: a cohort study.

机译:土耳其安塔利亚婴儿全面腹泻和持续腹泻的危险因素:一项队列研究。

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The aim of this study was to identify factors that influence the incidence of diarrhoea in infancy. The study was a prospective cohort study conducted in two primary healthcare unit areas in Antalya, Turkey. A total of 204 infants were followed until they were aged 1 year. Morbidity surveillance and anthropometric measurements were carried out by home visits every 2 months. The average incidences were found to be 2.76 episodes per child-year for overall diarrhoea and 18.56 episodes per 100 child-years for persistent diarrhoea. Relative risks, confidence intervals and logistic regression analyses were used to assess the associations. For both overall diarrhoea and persistent episodes, increased risks were associated with having an uneducated mother (RR=1.89 and 5.33, respectively) and a self-employed father (RR=1.89 and 3.77, respectively). Among environmental factors, living in a slum was associated with both overall (RR=1.68) and persistent (RR=2.69) diarrhoea, whereas living in a crowded house (RR=1.70), having no kitchen (RR=2.27) or having an unhygienic toilet (RR=1.93) were found to be significant for overall episodes alone. Factors related to the infant were preterm birth (RR=1.64), low birth weight (RR=2.05), and first breastfeed given more than 1 h after birth (RR=1.64). Nutritional status was also associated with overall or persistent diarrhoea: underweight children (RR=2.15, persistent diarrhoea only), stunted children (RR=1.67 and 2.14, respectively) or wasted children (RR=1.54 and 3.20, respectively). By logistic regression analysis, both overall and persistent diarrhoea were found to be associated with mother's education.
机译:这项研究的目的是确定影响婴儿腹泻发生率的因素。这项研究是在土耳其安塔利亚的两个主要医疗部门进行的前瞻性队列研究。总共追踪了204名婴儿,直到1岁。每2个月进行一次家访,进行发病率监测和人体测量。总体腹泻的平均发病率为每儿童年2.76次,持续性腹泻的发病率为每100儿童年18.56次。相对风险,置信区间和逻辑回归分析用于评估关联。对于总体腹泻和持续发作,母亲受过教育(分别为RR = 1.89和5.33)和自雇父亲(分别为RR = 1.89和3.77)会增加患病风险。在环境因素中,住在贫民窟与总体腹泻(RR = 1.68)和持续性腹泻(RR = 2.69)有关,而住在拥挤的房屋(RR = 1.70),没有厨房(RR = 2.27)或有腹泻的情况下。发现不卫生的厕所(RR = 1.93)仅对整个发作而言是重要的。与婴儿有关的因素包括早产(RR = 1.64),低出生体重(RR = 2.05)和出生后1小时以上首次母乳喂养(RR = 1.64)。营养状况也与总体或持续性腹泻有关:体重过轻的儿童(RR = 2.15,仅持续性腹泻),发育不良的儿童(分别为RR = 1.67和2.14)或消瘦的儿童(分别为RR = 1.54和3.20)。通过逻辑回归分析,发现总体腹泻和持续腹泻均与母亲的教育程度有关。

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