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首页> 外文期刊>Public health >Population-based study of small intestinal atresia and stenosis, Hawaii, 1986-2000.
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Population-based study of small intestinal atresia and stenosis, Hawaii, 1986-2000.

机译：基于人群的小肠闭锁和狭窄的研究，夏威夷，1986-2000年。

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Atresia and stenosis are some of the most common birth defects affecting the small intestine. Few population-based studies have examined the epidemiology of small intestinal atresia/stenosis. Eighty-two cases of small intestinal atresia/stenosis were identified through a population-based birth defects registry in Hawaii during 1986-2000. The relationships of various clinical and demographic factors with small intestinal atresia/stenosis and duodenal atresia/stenosis were examined. The small intestinal atresia/stenosis and duodenal atresia/stenosis rates were 2.9 per 10,000 live births [95% confidence interval (CI) 2.3-3.6] and 1.3 per 10,000 live births (95% CI 1.0-1.9), respectively. No secular trend was observed ( [Formula: see text] and 0.090, respectively). Maternal age risk for small intestinal atresia/stenosis was U-shaped, while duodenal atresia/stenosis rates were highest with maternal age of 35 years or more. Small intestinal atresia/stenosis was substantially more common among Far East Asiansthan Caucasians [rate ratio (RR) 1.96, 95% CI 1.24-2.94]. Duodenal atresia/stenosis risk was higher in Hawaii County than in Honolulu County (RR 2.55, 95% CI 1.10-5.02). Small intestinal atresia/stenosis was also associated with low birth weight (RR 11.50, 95% CI 8.05-15.92), low gestational age (RR 8.60, 95% CI 6.34-11.41) and multiple births (RR 3.79, 95% CI 1.39-8.24). In conclusion, this study found associations between small intestinal atresia/stenosis and maternal age, maternal race/ethnicity, county of residence, birth weight, gestational age and plurality, but not delivery period. Many of the associations between small intestinal atresia/stenosis and other factors noted in this investigation were similar to those reported by other studies.
机译：闭锁和狭窄是影响小肠的一些最常见的先天缺陷。很少有基于人群的研究检查小肠闭锁/狭窄的流行病学。在1986-2000年间，通过基于人群的出生缺陷登记系统在夏威夷确定了82例小肠闭锁/狭窄。研究了各种临床和人口统计学因素与小肠闭锁/狭窄和十二指肠闭锁/狭窄的关系。小肠闭锁/狭窄和十二指肠闭锁/狭窄的发生率分别为每10,000例活产2.9（95％置信区间（CI）2.3-3.6）和每10,000例活产1.3（95％CI 1.0-1.9）。没有观察到长期趋势（[公式：见正文]和0.090）。产妇年龄小肠闭锁/狭窄的风险呈U形，而十二指肠闭锁/狭窄的发生率最高于35岁或以上的母亲。在远东亚洲人中，小肠闭锁/狭窄比高加索人更为普遍[比率（RR）1.96，95％CI 1.24-2.94]。夏威夷县的十二指肠闭锁/狭窄风险高于檀香山县（RR 2.55，95％CI 1.10-5.02）。小肠闭锁/狭窄也与低出生体重（RR 11.50，95％CI 8.05-15.92），低胎龄（RR 8.60，95％CI 6.34-11.41）和多胎（RR 3.79，95％CI 1.39- 8.24）。总之，本研究发现小肠闭锁/狭窄与产妇年龄，产妇种族/族裔，居住县，出生体重，胎龄和复数之间有关联，但与分娩期无关。小肠闭锁/狭窄与本研究中提到的其他因素之间的许多关联与其他研究报道的相似。

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