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Trends in blood lipids and fat soluble vitamins in Catalonia, Spain (1992-2003)

机译:西班牙加泰罗尼亚的血脂和脂溶性维生素变化趋势(1992-2003年)

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OBJECTIVE: The purpose of this study was to assess the 10-year trend in lipid and antioxidant vitamin levels in the Catalan population from 1992 to 2003. DESIGN: Two cross-sectional surveys were carried out in Catalonia, Spain, during 1992-93 and 2002-03. A subsample of the individuals participating in the surveys agreed to undergo a biochemical evaluation. SUBJECTS: Eight hundred and eighty individuals (393 males and 487 females) in the 1992-93 nutritional survey and 429 individuals (205 males and 224 females) in the 2002-03 nutritional and health survey. The subjects' ages ranged from 18 to 74 years. RESULTS: Mean total cholesterol decreased from 5.3 to 5.1 mmol l-1 (P < 0.005), and the prevalence of hypercholesterolaemia decreased, especially in males (from 23% to 10% in males from 50 to 64 years old, P < 0.05). Mean cholesterol high-density lipoprotein (HDL) values decreased in the entire sample (from 1.4 to 1.3 mmol l-1, P < 0.001) and there was an increase in the percentage of population with low values of HDL (from 10% to 19%, P < 0.001). An increase in the percentage of the population with values of alpha-tocopherol at marginal risk levels (from 6% to 9%) and with low values of beta-carotene (from 59% to 66%) was observed. The mean values for retinol increased in both males (from 1.99 to 2.44 mummol l-1, P < 0.001) and females (from 1.69 to 2.29, P < 0.001).ConclusionAlthough there was a decrease in the percentage of population with hypercholesterolaemia, the decrease in HDL cholesterol worsened the lipid profile of the Catalan population. The increase in the values of some antioxidant vitamins did not affect the entire population since an increase in the number of individuals with marginal values was observed.
机译:目的:本研究的目的是评估加泰罗尼亚人从1992年至2003年的脂质和抗氧化维生素水平的10年趋势。设计:在1992-93年和2003年于西班牙加泰罗尼亚进行了两次横断面调查2002-03。参与调查的个人的子样本同意进行生化评估。主题:在1992-93年的营养调查中,有880个人(393名男性和487名女性)在2002-03年的营养与健康调查中有429个人(205男性和224女性)。受试者的年龄为18至74岁。结果:平均总胆固醇从5.3降至5.1 mmol l-1(P <0.005),高胆固醇血症的患病率下降,尤其是男性(从50岁到64岁的男性从23%下降到10%,P <0.05) 。整个样本中的胆固醇高密度脂蛋白(HDL)平均值下降(从1.4到1.3 mmol l-1,P <0.001),并且低密度脂蛋白值的人群百分比从10%上升到19 %,P <0.001)。观察到具有处于边缘风险水平的α-生育酚值(从6%到9%)和具有低水平的β-胡萝卜素(从59%到66%)的人口百分比增加。男性(从1.99到2.44μmmoll-1,P <0.001)和女性(从1.69到2.29,P <0.001)的视黄醇平均值均升高。结论尽管高胆固醇血症人群的百分比有所降低,但高密度脂蛋白胆固醇的降低使加泰罗尼亚人的血脂状况恶化。一些抗氧化剂维生素的价值增加并未影响整个人口,因为观察到具有边际价值的个体数量有所增加。

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