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首页> 外文期刊>Qualitative health research >Preserving the self: the process of decision making about hereditary breast cancer and ovarian cancer risk reduction.
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Preserving the self: the process of decision making about hereditary breast cancer and ovarian cancer risk reduction.

机译：保护自我：关于遗传性乳腺癌和卵巢癌风险降低的决策过程。

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Women who carry BRCA1 or BRCA2 (BRCA1/2) gene mutations have up to an 88% lifetime risk of breast cancer and up to a 65% lifetime risk of ovarian cancer. Strategies to address these risks include cancer screening and risk-reducing surgery (i.e., mastectomy and salpingo-oophorectomy). We conducted a grounded theory study with 22 BRCA1/2 mutation-carrier women to understand how women make decisions about these risk-reducing strategies. Preserving the self was the overarching decision-making process evident in the participants' descriptions. This process was shaped by contextual conditions including the characteristics of health services, the nature of hereditary breast and ovarian cancer risk-reduction decisions, gendered roles, and the women's perceived proximity to cancer. The women engaged in five decision-making styles, and these were characterized by the use of specific decision-making approaches. These findings provide theoretical insights that could inform the provision of decisional support to BRCA1/2 carriers.
机译：携带BRCA1或BRCA2（BRCA1 / 2）基因突变的女性，一生中罹患乳腺癌的风险高达88％，一生中罹患卵巢癌的风险高达65％。解决这些风险的策略包括癌症筛查和降低风险的手术（即乳房切除术和输卵管卵巢切除术）。我们对22位BRCA1 / 2突变携带者女性进行了扎根的理论研究，以了解女性如何做出有关降低风险策略的决策。保存自我是参与者描述中显而易见的总体决策过程。这一过程是由上下文条件决定的，这些条件包括卫生服务的特征，遗传性乳腺癌和卵巢癌降低风险的决策的性质，性别角色以及女性对癌症的亲近感。妇女从事五种决策风格，其特征是使用特定的决策方法。这些发现提供了理论上的见识，可以为BRCA1 / 2航空母舰提供决策支持。

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