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首页> 外文期刊>Umweltmedizin in Forschung und Praxis >Sensitization to Allergens of Ambrosia artemisiifolia and other Allergens on 10 years old Children and Adults in Baden-Wurttemberg
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Sensitization to Allergens of Ambrosia artemisiifolia and other Allergens on 10 years old Children and Adults in Baden-Wurttemberg

机译：巴登-符腾堡州10岁儿童和成年人对青蒿和其他过敏原的过敏原致敏

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摘要

Since 1992, the sentinel health public offices have carried out allergy screenings on school children of grade 4 (approximately 9-10 years old) from the state of Baden Wuerttemberg. Allergy screenings for Ambrosia artemisiifolia have been included since 2004 and since 2006 screenings forthemajorallergenofragweed and mugwort Amba 1 and Artv 1 have been included as well. From 2004 to 2009 a total of 2.678 children and from 2008 to 2009 a total of 1.134 adults were tested. Approximately 37% of all children tested were sensitized against the inhalative allergen of the sx1 -Tests,about 15% were sensitized against the native Ambrosia artemisiifolia-allergen, about 3% were sensitized against the major allergen of Ambrosia (Amb a 1) and approximately 5% were sensitized against the native major allergen of mugwort (Art v 1 ).The sensitization rate of the adults tested was approximately the same as that of the children exceptforthe sensitization against Amb a 1, where less than 1% of the tested adults showed signs of sensitization. There was a high cross reaction of the native Ambrosia artemisiifolia-allergen with the native mugwort-allergen as well as other allergens. However, the data on such positive sensitization does not necessarily involve a clinical relevance. Only a suitable differential diagnosis may give answers on the clinical importance. Even though from the current state of spread of Ambrosia no conclusion can be drawn on potential health risks, thefurther spreading of Ambrosia should be prevented in the terms of the precautionary principle and of the consideration of proportionality.
机译：自1992年以来，前哨卫生局对来自巴登符腾堡州的4年级（约9-10岁）学龄儿童进行了过敏检查。自2004年以来，已包括对青蒿的过敏性筛查，自2006年以来，还包括对潮草，艾草，艾蒿1和Artv 1的筛查。从2004年至2009年，共测试了2.678名儿童，从2008年至2009年，共测试了1.134名成人。大约37％的受测儿童对sx1-Tests的吸入性过敏原致敏，约15％对天然的Ambrosia artemisiifolia-allergen致敏，约3％对Ambrosia的主要致敏原（Amb a 1）致敏， 5％的人对艾蒿的主要主要过敏原致敏（第1条）。除了对Amb a 1的致敏性（其中不到1％的成年人显示）以外，测试的成年人的致敏率与儿童大致相同。致敏的迹象。天然青蒿-过敏原与艾蒿-过敏原以及其他过敏原之间存在高度交叉反应。但是，有关这种阳性致敏性的数据并不一定涉及临床。只有适当的鉴别诊断才能给出临床重要性的答案。即使从目前尚存的散布状态无法得出任何潜在的健康风险的结论，但应从预防原则和考虑相称性的角度，防止散布的进一步散布。

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