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Changes in regional cerebral blood flow after body image exposurein eating disorders

机译:饮食失调的人体图像暴露后局部脑血流量的变化

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摘要

Relationships of 'perceptual distortion' and 'cognitive evaluation' components of body image disturbances to brain activity were investigated. Changes in regional cerebral blood (rCBF) of nine patients with anorexia nervosa restrictive type (AN), 13 patients with bulimia nervosa purging type (BN) and 12 controls following three experiments with single photon emission computed tomography (SPECT) were compared: at rest, following a landscape video presentation (neutral stimulus), and after their filmed body image (positive stimulus) exposure. Body distortion was measured with the Silhouette test and body dissatisfaction with the Body Shape Questionnaire (BSQ). Patients with AN showed a hyperactivation of the left parietal and right superior frontal from neutral to positive stimulus. Patients with BN showed a hyperactivation of the right temporal and right occipital areas. Changes in BSQ responses were associated with changes in the right inferior frontal and right temporal rCBF, whereas changes in body distortion were related to the left parietal. The activation of the right temporal after the own body image exposure might be in accordance with the aversive events' response. Functional abnormalities in AN might be related to the storage of a distorted prototypical image of the body in the left parietal lobe.
机译:研究了身体影像障碍的“知觉失真”和“认知评估”成分与大脑活动的关系。比较了三项单光子发射计算机断层扫描(SPECT)实验后,对9例神经性厌食症限制性类型(AN),13例贪食性贪食症清除类型(BN)和12例对照的局部脑血(rCBF)的变化:静止,进行横向视频演示(中性刺激)以及拍摄他们拍摄的身体图像(积极刺激)之后。身体变形通过Silhouette测试进行测量,身体对身体形状调查表(BSQ)不满意。 AN患者从中性刺激到阳性刺激均显示左顶叶和右上额叶过度活化。 BN患者表现出右侧颞叶和右侧枕叶区域的过度活化。 BSQ反应的变化与右下额叶和右颞rCBF的变化有关,而身体变形的变化与左顶叶的变化有关。自身图像曝光后右颞的激活可能与厌恶事件的反应一致。 AN中的功能异常可能与身体变形的原型图像存储在左顶叶中有关。

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