Cortico-subcortical underpinnings of narrative processing impairment in schizophrenia

Gianfranco Spalletta; Ilaria Spoletini; Andrea Cherubini; Ivo Alex Rubino; Alberto Siracusano; Fabrizio Piras; Carlo Caltagirone; Andrea Marini

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Cortico-subcortical underpinnings of narrative processing impairment in schizophrenia

机译：精神分裂症的叙事处理障碍的皮质下皮质基础。

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Cortical and subcortical gray matter volumes were correlated with a set of linguistic scores in a group of schizophrenia patients. Lexical informativeness was positively associated with the volume of the left frontal cortical and accumbal areas, while left hippocampal atrophy and right ventricle enlargement predicted increased production of semantic paraphasias. Global coherence impairment was predicted by left accumbal volume reduction and left ventricle enlargement. These data confirm that the brain structure of specific cortical and subcortal areas, as determined by magnetic resonance imaging, is related to the compromised semantic retrieval and language control in schizophrenia.

机译：在一组精神分裂症患者中，皮层和皮层下灰质体积与一组语言评分相关。词汇信息量与左额叶皮质和and区域的体积呈正相关，而左海马萎缩和右心室扩大则预示着语义性妄想的产生增加。总体相干性损害可通过左accu体积减小和左心室增大来预测。这些数据证实，通过磁共振成像确定的特定皮质和皮质下区域的大脑结构与精神分裂症中受损的语义检索和语言控制有关。

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《Psychiatry Research. Neuroimaging》 |2010年第1期|共4页
作者
Gianfranco Spalletta; Ilaria Spoletini; Andrea Cherubini; Ivo Alex Rubino; Alberto Siracusano; Fabrizio Piras; Carlo Caltagirone; Andrea Marini;
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正文语种 eng
中图分类神经病学与精神病学;
关键词
Schizophrenia; Language; narrative; Gray matter volumes; MRI;

机译：精神分裂症;语言;叙述;灰质体积;MRI;

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1. Cortico-subcortical underpinnings of narrative processing impairment in schizophrenia [J] . Gianfranco Spalletta, Ilaria Spoletini, Andrea Cherubini, Psychiatry Research. Neuroimaging . 2010,第1期

机译：精神分裂症的叙事处理障碍的皮质下皮质基础。
2. Interleukin-6: the missing element of the neurocognitive deterioration in schizophrenia? The focus on genetic underpinnings, cognitive impairment and clinical manifestation [J] . Frydecka Dorota, Misiak Blazej, Pawlak-Adamska Edyta, European archives of psychiatry and clinical neuroscience . 2015,第6期

机译：白细胞介素6：精神分裂症神经认知恶化的缺失要素？关注遗传基础，认知障碍和临床表现
3. Understanding the pathological mechanisms underpinning functional impairments in schizophrenia: Gamma oscillations versus mismatch negativity (MMN) as mediating factors [J] . HarmsL.R., MichieP.T. Clinical neurophysiology . 2013,第11期

机译：了解精神分裂症功能障碍的病理机制：γ振荡与失配负性（MMN）作为中介因子
4. KOTOBAKARI Study: Using Natural Language Processing of Patient Short Narratives to Detect Cancer Related Cognitive Impairment [C] . Eiji Aramaki, Mai Miyabe, Chihiro Honda, MEDINFO . 2019

机译：Kotobakari研究：利用患者短篇叙事的自然语言处理来检测癌症相关的认知障碍
5. Elucidating Working Memory Impairment in Schizophrenia: Task-Switching as an Underlying Mechanism. [D] . Buchholz, Alison. 2017

机译：阐明精神分裂症的工作记忆障碍：任务转换是一种基本机制。
6. Interleukin-6: the missing element of the neurocognitive deterioration in schizophrenia? The focus on genetic underpinnings cognitive impairment and clinical manifestation [O] . Dorota Frydecka, Błażej Misiak, Edyta Pawlak-Adamska, -1

机译：白细胞介素6：精神分裂症神经认知恶化的缺失要素？重点关注遗传基础认知障碍和临床表现
7. Cortico-subcortical underpinnings of narrative processing impairment in schizophrenia [O] . Spalletta G, Spoletini I, Cherubini A, 2010

机译：精神分裂症的叙事处理障碍的皮质下皮质基础。

Cortico-subcortical underpinnings of narrative processing impairment in schizophrenia

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