• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Psychiatry Research. Neuroimaging >Psychomotor symptoms of schizophrenia map on the cerebral motor circuit
【24h】

Psychomotor symptoms of schizophrenia map on the cerebral motor circuit

机译：精神分裂症的精神运动症状在大脑运动回路中的分布图

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Schizophrenia is a devastating disorder thought to result mainly from cerebral pathology. Neuroimaging studies have provided a wealth of Findings of brain dysfunction in schizophrenia. However, we are still far from understanding how particular symptoms can result from aberrant brain function. In this context, the high prevalence of motor symptoms in schizophrenia such as catatonia, neurological soft signs, parkinsonism, and abnormal involuntary movements is of particular interest. Here, the neuroimaging correlates of these motor symptoms are reviewed. For all investigated motor symptoms, neural correlates were found within the cerebral motor system. However, only a limited set of results exists for hypokinesia and neurological soft signs, while catatonia, abnormal involuntary movements and parkinsonian signs still remain understudied with neuroimaging methods. Soft signs have been associated with altered brain structure and function in cortical premotor and motor areas as well as cerebellum and thalamus. Hypokinesia is suggested to result from insufficient interaction of thalamocortical loops within the motor system. Future studies are needed to address the neural correlates of motor abnormalities in procdromal states, changes during the course of the illness, and the specific pathophysiology of catatonia, dyskinesia and parkinsonism in schizophrenia. (C) 2015 Elsevier Ireland Ltd. All rights reserved.
机译：精神分裂症是一种破坏性疾病，被认为主要是由脑部病理学引起的。神经影像学研究为精神分裂症的脑功能障碍提供了丰富的发现。但是，我们仍然不了解异常的脑功能如何导致特定症状。在这种情况下，精神分裂症中运动症状的高患病率尤其令人关注，例如精神紧张症，神经软体征，帕金森病和异常的非自愿运动。在这里，这些运动症状的神经影像相关性进行了审查。对于所有调查的运动症状，均在大脑运动系统内发现了神经相关性。但是，对于运动不足和神经系统软体征只有有限的一组结果，而神经影像学方法仍未充分研究卡塔托尼亚，异常不自主运动和帕金森氏体征。柔软的体征与皮质运动前和运动区以及小脑和丘脑的大脑结构和功能改变有关。运动功能减退是由于运动系统内丘脑皮层环相互作用不足引起的。需要进一步的研究来解决无脊椎动物状态下运动异常，疾病过程中的变化以及精神分裂症中卡塔顿尼亚，运动障碍和帕金森氏症的特定病理生理学的神经相关性。 （C）2015 Elsevier Ireland Ltd.保留所有权利。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号