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首页> 外文期刊>Psychiatry Research. Neuroimaging >Reduced insular volume in attention deficit hyperactivity disorder
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Reduced insular volume in attention deficit hyperactivity disorder

机译：注意缺陷多动障碍的胰岛体积减少

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The aim of this study was to evaluate whether structural differences in the insula and anterior cingulate cortex (ACC), two critical areas of the "salience network," co-exist in adolescents with attention deficit hyperactivity disorder (ADHD) compared with healthy controls (HC). In addition we aimed to determine if structural changes within these regions correlate with attention and inhibitory function. Nineteen adolescents with ADHD and 25 HC received MRI scans on a 3. T magnet. Morphometric analysis was performed with FreeSurfer. Youths with ADHD were found to have a bilateral reduction in anterior insular (AIC) gray matter volumes compared to HC. Furthermore, the left AIC was found to positively correlate with oppositional symptoms, while the right AIC was found to associate with both attention problems and inhibition. To our knowledge this is the first report of a bilateral reduction in AIC volumes in ADHD. Our findings suggest a role for the insula in modulating attention and inhibitory capacity in ADHD.
机译：这项研究的目的是评估与健康对照相比，患有注意缺陷多动障碍（ADHD）的青少年是否同时存在岛突和前扣带回皮质（ACC）的两个结构，即“显着网络”的两个关键区域。 HC）。此外，我们旨在确定这些区域内的结构变化是否与注意力和抑制功能相关。 19名患有ADHD和25 HC的青少年在3. T磁铁上接受了MRI扫描。用FreeSurfer进行形态分析。与HC相比，发现患有ADHD的年轻人双侧前岛（AIC）灰质减少。此外，发现左AIC与对立症状正相关，而发现右AIC与注意问题和抑制都相关。据我们所知，这是关于多动症中双侧AIC量减少的首次报道。我们的研究结果提示了岛突在调节注意力缺陷多动症的注意力和抑制能力中的作用。

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