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Trajectories of Depressive Symptoms in Old Age: Integrating Age-, Pathology-, and Mortality-Related Changes

机译:老年抑郁症状的轨迹:整合年龄,病理和死亡率相关的变化

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Late life involves a variety of different challenges to well-being. This study extends and qualifies propositions drawn from the paradox of well-being in aging using 15-year longitudinal data on depressive symptoms from old and very old participants in the Australian Longitudinal Study of Ageing (Baseline N = 2,087; M-age = 78.69 years; range: 65-103 years; 49.40% women). We first examined age-related trajectories in depressive symptoms from young-old to oldest-old, taking into account (changes in) relevant correlates, pathology, and mortality; and, second, we investigated gender differences in these trajectories. Results revealed that age-related trajectories of depressive symptoms were predictive of mortality hazards. The unique predictive effects of both level of, and change in, depressive symptoms were independent of one another and held after taking into account education as well as changes in marital status, living arrangements, cognitive function, and illness burden. In addition, results indicated that depressive symptoms were elevated among participants suffering from arthritis, and increased with age more markedly in men than in women. In particular, the significant Age x Gender interaction indicated that the gender gap in depressive symptoms reduced from young-old to old-old and reversed in very old age when men showed more depressive symptoms than women. Qualifying the paradox of well-being in aging, findings demonstrated that depressive symptoms increased from young-old to oldest-old and suggest that age-, pathology-, and mortality-related changes should be examined in concert to advance our understanding of individual differences in depressive symptom trajectories in late life.
机译:晚年生活涉及对幸福的各种不同挑战。这项研究使用来自澳大利亚衰老纵向研究的15年纵向和老年参与者的抑郁症状纵向数据(基线N = 2,087; M-年龄= 78.69岁),扩展并验证了由老年健康悖论得出的命题;范围:65-103岁;女性占49.40%)。我们首先研究了年龄相关的抑郁症状从年轻到老的轨迹,同时考虑了相关的相关因素,病理和死亡率。其次,我们研究了这些轨迹中的性别差异。结果显示,与年龄相关的抑郁症状轨迹可预测死亡危险。抑郁症状的水平和变化的独特预测作用彼此独立,并且在考虑到教育以及婚姻状况,生活安排,认知功能和疾病负担的变化之后才得以保持。另外,结果表明,患有关节炎的参与者的抑郁症状升高,并且随着年龄的增长,男性比女性更明显。特别是,显着的年龄x性别交互作用表明,抑郁症状中的性别差距从年轻到老年逐渐缩小,并在很老的年龄中有所逆转,此时男性表现出比女性更多的抑郁症状。研究发现,抑郁症的症状从年轻到最老的年龄增加了,这证明了老年人的幸福悖论,并建议应与年龄,病理学和死亡率相关的变化共同研究,以增进我们对个体差异的理解在晚年的抑郁症状轨迹中。

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