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首页> 外文期刊>Psychosomatic Medicine: Journal of the American Psychosomatic Society >Lower lipid peroxide levels in practitioners of the Transcendental Meditation program.
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Lower lipid peroxide levels in practitioners of the Transcendental Meditation program.

机译：超越冥想计划的从业者降低脂质过氧化物的水平。

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OBJECTIVE: Oxidative stress or free radical activity may contribute to the pathophysiology of atherosclerosis and other chronic diseases associated with aging. Because psychosocial stress has been shown to increase oxidative stress, we conducted an exploratory study to investigate the effects of stress reduction with the Transcendental Meditation program on serum lipid peroxide levels in elderly subjects. METHOD: Forty-one normally healthy subjects (aged 56 to 74 years, average 67 years) were recruited from the same Midwest city. Eighteen were long-term practitioners of the TM program (average 16.5 years). Twenty-three controls were not practicing a formal stress management technique. Venous blood samples were analyzed for lipid peroxides by the TBARS assay. A dietary questionnaire was used to assess fat intake, red meat consumption, antioxidant vitamin supplementation, and smoking. Differences between groups and subgroups were analyzed by t test, and correlations. RESULTS: Significantly lower serum levels of lipid peroxides were found in the TM practitioners compared with controls (-15%, p = .026). No significant differences were found between groups on smoking, fat intake, or vitamin supplementation. TM practitioners also had lower red meat consumption but matched subgroup analysis and partial correlations did not confirm a relationship between red meat intake and lipid peroxide levels. CONCLUSIONS: These preliminary findings suggest that lower serum lipid peroxide levels may be associated with stress reduction using the Transcendental Meditation technique. Prospective controlled trials are needed to confirm that this effect is because of TM practice rather than other lifestyle factors, such as diet.
机译：目的：氧化应激或自由基活性可能有助于动脉粥样硬化和其他与衰老相关的慢性疾病的病理生理。由于已经显示出社会心理压力会增加氧化压力，因此我们进行了一项探索性研究，以研究通过先行冥想计划减轻压力对老年受试者血清脂质过氧化物水平的影响。方法：从同一中西部城市招募了41名正常健康的受试者（年龄56至74岁，平均67岁）。 TM计划的长期从业人员为18人（平均16.5年）。 23个控件未采用正式的压力管理技术。通过TBARS测定法分析静脉血样品中的脂质过氧化物。饮食调查表用于评估脂肪摄入，红肉消耗，抗氧化维生素补充和吸烟。通过t检验和相关性分析组与亚组之间的差异。结果：TM执业者的血清过氧化物脂质水平明显低于对照组（-15％，p = .026）。吸烟，脂肪摄入或补充维生素的两组之间无显着差异。 TM从业者的红肉消耗量也较低，但匹配的亚组分析和部分相关性未确认红肉摄入量与脂质过氧化物水平之间的关系。结论：这些初步发现表明，使用先验冥想技术降低血清脂质过氧化物水平可能与减轻压力有关。需要进行前瞻性对照试验，以确认这种效果是因为TM的做法而不是饮食等其他生活方式因素引起的。

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